摘要
目的观察甲状腺自身抗体(ATA)及促甲状腺激素(TSH)对复发性流产(RSA)的影响。方法选取我院118例早期妊娠患者进行常规检查甲状腺功能,其中73例既往有过2次以上不明原因的流产史患者作为研究组,并以45例既往无不良妊娠史的育龄妇女作为对照组。结果RSA患者中甲状腺抗体ATA,TPOAb,TGAb阳性率与对照组相比较,P<0.05,均有统计学差异;甲状腺抗体阳性且伴有促甲状腺激素(TSH)≥3.93mIU的流产率为83.33%与单纯性甲状腺抗体阳性的患者流产率23.53%比较,P<0.05,两组比较有统计学差异。结论甲状腺自身抗体阳性与复发性流产关系密切,TSH升高是流产的危险因子,建议两者为孕早期常规筛查。
Objective To study thyroid autoantibodies （ ATA） and thyroid stimulating hormone TSH for re-current miscarriage （ RSA） effects.Methods One hundred and eighteen cases of early pregnancy in our hospital for rou-tine examination of thyroid function in patients were chosen ,including 73 cases with a history of more than 2 unexplained miscarriages as the study group ,and 45 cases with no previous history of adverse pregnancy women of childbearing age as a control groups .Results Thyroid antibodies ATA ,TPO-Ab,TG-Ab in RSA patients were differente ,compared with the control group（ P〈0.05）;The abortion rate in patiengts with thyroid antibodies associated with thyroid-stimulating hor-mone（TSH）≥3.93mIU was 83.33%and the abortion rate in simple thyroid antibody positive patients was 23.53%.It showed the significant difference （ P〈0 .05 ） .Conclusion Thyroid autoantibodies are related to recurrent miscarriage , and TSH is elevated as a miscarriage risk factors .They are recommend as routine screening of early pregnancy .
出处
《潍坊医学院学报》
2013年第6期468-470,共3页
Acta Academiae Medicinae Weifang
关键词
甲状腺自身抗体
TSH
流产
复发性
TSH
Thyroid Autoantibodies
Recurrent spontaneous abortion
