摘要
目的观察第三代头孢菌素类药物在临床应用中的不良反应情况。方法随机选择我院进行常规静脉注射治疗的患者1900例,对他们使用第三代头孢菌素类药物进行临床治疗,并就患者的不良反应情况进行统计、比较和分析。结果临床分析显示,第三代头孢菌素类药物在临床应用中的不良反应发生率为2.89%,且以过敏反应(56.34%)为主。头孢他啶产生的不良反应最少,且所有不良反应的发生同患者的性别、年龄均无明显的关联性(P>0.05)。结论在进行第三代头孢菌素类药物的临床应用时,要在关注抗菌效应的同时,注重患者用药的不良反应,从而确保药物应用的正确性,提高患者的临床治疗效果,避免出现药物滥用现象。
Objective To observe the adverse reaction of the third generation cephalosporins in clinical application. Methods Our hospital 1900 cases of conventional intravenous injection in the treatment of patients for clinical treatment, to their use of third generation cephalosporins, and adverse reactions were statistics, comparison and analysis. Results Clinical analysis showed, adverse reactions of the third generation cephalosporins in clinical application rate was 2.89%, and the allergic reactions （56.34%）. The adverse reaction of ceftazidime have the least, and the occurrence of sex, age and patients of all adverse reactions had no clear correlation （P〉0.05）. Conclusion In the clinical application of the third generation of cephalosporins, focus on the antibacterial effect and adverse reaction of patients with medication, so as to ensure the correctness of drug application, improve the clinical treatment effect of patients and avoid the misuse of medicines.
出处
《中国医药科学》
2013年第24期84-85,共2页
China Medicine And Pharmacy
关键词
头孢菌素类药物
第三代
临床应用
不良反应
Cephalosporins
The third generation
Clinical application
Adverse reaction
