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呼吸机相关性肺炎:从指南到实践 被引量:31

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摘要 目前,根据呼吸机相关性肺炎(VAP)定义和患者人群不同,VAP在全球范围内的发病率为6%~52%或(1.6~52.7)例/1 000机械通气日,病死率为14%~50%.VAP导致重症医学科(ICU)留治时间延长、住院费用增加,且是危重症患者重要的致死原因.近十年来,美国、英国、加拿大等国家相继出台了VAP相关的诊疗指南[1-4],VAP防治取得了长足进步,发病率不断下降,在美国甚至有呼声将VAP纳入政府医疗保险机构拒绝支付目录.而我国VAP的高发病率和高死亡率形势仍旧严峻,如何遏制VAP已成为临床医学领域亟待解决的重大课题.近日,中华医学会重症分会发布了〈呼吸机相关性肺炎预防、诊断和治疗指南(2013)>[5](以下均简称〈VAP指南>).其借鉴了国内外主要学术组织如美国重症医学会及胸科协会、英国抗微生物及化学治疗协会等制定指南的经验,基于临床常见及热点问题,结合近年来的研究进展,应用循证医学的方法,重点对呼吸机相关性肺炎的预防、诊断和治疗方面进行了详细的介绍.
作者 黎毅敏
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第5期321-323,共3页 National Medical Journal of China
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