摘要
目的探讨季节变化对自身免疫性甲状腺疾病(AITD)发病的影响。方法 1142例AITD患者中,格雷夫斯病(GD)904例,桥本甲状腺炎(HT)171例,萎缩性甲状腺炎(AT)67例,采用圆形分布分析法分析不同季节的AITD发病数及季节变化对甲状腺激素水平的影响。结果 AITD在春季发病数最高。GD患者甲状腺激素水平并未表现出明确的季节相关性,但2月份的甲状腺激素水平明显高于7月份。慢性淋巴细胞性甲状腺炎(包括HT、AT)患者甲状腺激素水平出现明确的冬高、夏低的现象(P<0.05)。结论 AITD发病存在季节相关性,表现出春季高发的特点。临床上可根据季节变化适当调整个体治疗方案。
Objective To investigate the relationship of seasonal variation with autoimmune thyroid diseases（AITD）. Methods Of 1142 patients with AITD, 904 patients were with Graves＇ diseases（GD）, 171 patients with Hashimoto thyroiditis（HT） and 67 patients with atrophic thyroiditis （AT）. The circular distribution analysis was performed to study the incidence of seasonal variation of AITD. Results The morbility of AITD was the highest in Spring. Serum levels of thyroid hormone in GD patients had no significant seasonal variation, but were higher in February than that in July, which in chronic lymphocytic thyroiditis including HT and AT were higher in Winter than those in Summer （P〈0. 05）. Conclusion The incidence of seasonal variation of AITD exists, which is manifested by higher morbility in Spring. Individual treatment programs should be adjusted according to seasonal changes.
出处
《江苏医药》
CAS
北大核心
2014年第3期313-316,共4页
Jiangsu Medical Journal
