摘要
为了探讨复方板蓝根制剂对小鼠生长性能和免疫力的影响,以便为开发中药免疫增强剂提供实验依据。将100只21日龄、质量相近、健康状况良好的小鼠随机分为10组:Ⅰ组为空白对照组,饲喂常规饲料;Ⅱ和Ⅲ组为黄霉素对照组和黄芪多糖对照组,分别饲喂添加1.0 g/kg黄霉素和1.0 g/kg黄芪多糖的饲料;Ⅳ-Ⅶ组为板蓝根对照组、鱼腥草对照组、陈皮对照组和黄芪对照组,分别饲喂添加1.0 g/kg相应药物的饲料;Ⅷ-Ⅹ组为试验组,分别饲喂添加0.5 g/kg、1.0 g/kg和1.5 g/kg复方板蓝根的饲料。结果表明,Ⅹ组小鼠的料肉比显著降低,日增重显著提高,力竭游泳时间显著延长(P<0.05);Ⅸ组小鼠的免疫细胞水平明显提高,肝指数明显增加;Ⅷ组小鼠的脾指数增加最为明显。提示复方板蓝根制剂能提高小鼠的生长性能,并增强小鼠的免疫力。
In order to study the effect of compound Radix Isatidis prescription on the growth perlormance and immunity of mice, so as to provide the experimental basis tot the. development of Chinese medicine immunoenhancer, 100 healthy mice with similar body weights were randomly divided into 10 groups with 10 in each group. Group I was the control group and fed with normal feed without any medicine, group II was flavomycin control group and added with 0.1% of flavomycin, group IH was Astragalus polysaccharide control group and fed with 0.1% of Astragalus polysaccharide, group IV to VII was the single herb-medicine group and fed with 0.1% of Rculix lsatidis,Herba Houttuyniae, Pericarpium Cirri Reticulatae and Radix Astragali, respectively. Group III to X was the trial group and added with 0.05%, 0.1% and 0.15% of compound Radix lsatidis prescription, respectively. After 20 days, the relevant indexes were determined. The results showed that compared with lhe control group, the growth performance and exhaustive swimming time of mice in group X was significantly increased, the immune cell levels and liver index of mice in group IX was obviously increased, and the spleen index of mice in group VIII was increased. It prompts that compound Radix Isaidis prescription couht increase the growth performance and immunity of mice to some extent.
出处
《中兽医医药杂志》
2014年第1期43-47,共5页
Journal of Traditional Chinese Veterinary Medicine
基金
国家大学生创新项目(SCX1222)
关键词
复方板蓝根制剂
小鼠
生长性能
免疫力
compound Radix Isatidis prescription
mice
growth performance
immune function
