摘要
目的了解植生克雷伯菌在绍兴市人民医院的感染现状,以及该菌的耐药特点,为临床合理用药提供依据。方法收集本院2012年6月-2013年6月分离鉴定的69株植生克雷伯菌,采用纸片扩散法(K-B法)和微量稀释法测定24种抗菌药物的敏感情况,用WHONET5.4软件进行分析。结果本院植生克雷伯菌主要分布于神经外科病房,且对大多数抗生素具有较高的耐药性,对氨苄西林和哌拉西林的耐药率最高(耐药率>98%),仅对呋喃妥因、复方新诺明、哌拉西林/他唑巴坦及亚胺培南显示了较好的体外活性,敏感率依次为98.55%、94.2%、89.86%及85.51%。结论植生克雷伯菌为多重耐药菌,临床应根据药敏结果合理用药,控制和减少感染的发生。
Objective To investigate the current infection status and antibiotic resistance of Klebsiella planticola isolates from Shaoxing People＇s Hospital and provide basis for rational clinical medication. Methods A total of 69 strains of KlebsieUa plan- ticola were isolated from the hospital from June 2012 to June 2013. The antibiotic susceptibility to 24 kinds of antibiotics were tested by K - B method and micro - dilution method, then the test results were analyzed by Whonet 5. 4 software. Results Klebsiella planticola was mainly distributed in neurosurgery department, showing highly drug resistance to most of the antibiotics. The drug resistance rate to ampicillin and piperacillin reached above 98%. It showed a better activity to furantoin, trimetboprim- suffamethoxazo, piperacilhn/sulbaetam and imipenem in ,＋itro, and the sensitive rates were 98.55% , 94.2% , 89.86% and 85.51%, respectively. Conclusion KlebsieUa planticola isolates from the hospital showed high resistance to many antibiotics. So clinical medication should be in accordance with the antibiotic susceptibility results, in order to control and reduce the incidence of infection.
出处
《中国卫生检验杂志》
北大核心
2014年第3期437-438,共2页
Chinese Journal of Health Laboratory Technology
关键词
植生克雷伯菌
耐药性
神经外科
Klebsiella planticola
Antibiotic resistance
Neurosurgery department
