期刊文献+

阿加曲班联合参芎葡萄糖治疗进展性脑梗死35例 被引量:5

Argatroban and ShenXiong Glucose for 35 Cases of Progressive Cerebral Infarction
下载PDF
导出
摘要 目的:观察阿加曲班联合参芎葡萄糖治疗进展性脑梗死的临床疗效。方法:将70例进展性脑梗死患者随机分为治疗组和对照组各35例,治疗组给予阿加曲班和参芎葡萄糖联合常规治疗,对照组给予常规治疗,疗程为14天。观察2组治疗前、后美国国立卫生院卒中量表(NIHSS)评分和日常生活活动能力Barthel指数(Barthel)。结果:总有效率治疗组为91.43%,对照组为80.00%。2组相比差异显著(P<0.05)。NIHSS评分和Barthel指数治疗后2组均明显改善(P<0.05),但治疗组改善更明显(P<0.05)。结论:早期应用阿加曲班联合参芎葡萄糖能提高临床有效率,改善进展性脑梗死的神经功能缺损和日常生活能力。 Objective:To investigate clinical effects of argatroban and ShenXiong glucose in treating progres-sive cerebral infarction. Methods:All 70 patients were randomly allocated into the treatment group and the control group, the treatment group accepted routine treatment, argatroban and ShenXiong glucose, and the control group rou-tine treatment, one course of the treatment was 14 days. The scales of NIHSS, daily living ability and Barthel index of both groups were observed before and after treating. Results: Total effective rate of the treatment group was 91.43%, higher than 80.00% of the control group, the difference was significant (P&lt;0.05). NIHSS scales and Barthel indexes were improved significantly after treating (P&lt;0.05), and the improvement of the treatment group was more significant (P&lt;0.05). Conclusion:Argatroban applied in the early time and ShenXiong glucose could im-prove clinical effective rate, improve neurologic impairment and daily living ability.
作者 焦富成
机构地区 庆阳市人民医院
出处 《西部中医药》 2014年第2期112-113,共2页 Western Journal of Traditional Chinese Medicine
关键词 脑梗死 进展性 阿加曲班 参芎葡萄糖 cerebral infarction,progressive Argatroban ShenXiong glucose
  • 相关文献

参考文献10

二级参考文献23

共引文献15815

同被引文献46

  • 1各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33029
  • 2脑卒中患者临床神经功能缺损程度评分标准(1995)[J].中华神经科杂志,1996,29(6):381-383. 被引量:15752
  • 3Kurisu K, Kawabori M, Niiya Y, et al. Pituital apoplexy man- ifesting as massive inlxacerebral hemorrhage [ J ]. Neurol Med Chit(Tokyo) ,2012,52(8) :587-590.
  • 4Mohind_ra S, Rane S, Gupta SK. Symptomatic apoplexy in intr- amedullary ependymoma: a report of a pediatric patient [ J ]. Pediatr Neurosurg, 2011,47 ( 5 ) : 369 -371.
  • 5Nilasena DS, Kresowih b-T, Wiblin RT, et al. Assessing pat- terns of tPA use in acute stroke[ J ]. Stroke,2002,33 ( 1 ) :354.
  • 6Bea F, Kreuzer J, Preusch M, et al. Melagatran reduces ad- vanced atherosclerotic lesion size and may promote plaque sta- bility in apolipoprotein E deficient mice [ J ]. Arterioseler Thromb Vase Biol,2006,26(12) :2787-2792.
  • 7Nakamura T, Kuroda Y, Hosomi N, et al. Serinepmtease inhib- itor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat [ J ]. Aeta Neuroehir S uppl, 2010, 106:307-310.
  • 8Engstrom M, Rundgren M, Sehott U, et al. An evaluation of monitoring possibilities of argatrohan using rotational throm- hoelastometry and activated partial thromboplastin time [ J ]. Acta Anaesthesiol Scand,2010,54:86-91.
  • 9I-Ieldner, MR., Zubler, C, Mattle HP. National institutes of healthstroke scale score and vessel occlusion in 2152 patients with acute is- chemic stmke[J].Stroke,2013,44(4) : 1153-1157.
  • 10Xia CF,Yin H, Borlongan CV, et al.Kallikrein gene transfer protects a- gainst ischemie stroke by promoting glial cell migration and inhibiting apoptosis[J].Hypertension, 2004( 43 ) : 452--459.

引证文献5

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部