摘要
目的探讨肠脂肪酸结合蛋白(I-FABP)在急性肠梗阻患者肠缺血坏死诊断中的价值。方法选取于该院治疗的128例急性肠梗阻患者(肠梗阻组),其中发生肠缺血坏死的患者53例(缺血坏死组),未发生肠缺血坏死的患者75例(非缺血坏死组),同期130例健康体检者作为对照组。对上述人群的血清I-FABP水平进行比较分析。结果肠梗阻组血清I-FABP水平和I-FABP的阳性率均高于对照组(P<0.05),缺血坏死组血清I-FABP水平和I-FABP阳性率均高于非缺血坏死组(P<0.05)。I-FABP检测用于诊断急性肠梗阻患者肠缺血坏死的ROC曲线下面积为0.805(95%CI:0.772~0.938,P<0.05)。结论 IFABP在肠梗阻患者肠缺血坏死的诊断中有较高的应用价值,值得推广。
Objective To study the value of I-FABP in discriminating intestinal ischemic in patients with acute intestinal ob- struction. Methods We compared and analyzed the level of serum 1-FABP in 128 patients with acute intestinal obstruction （ische- mic group 53 cases,non-ischemic group 75 cases） and 130 healthy people （the control group）. Results The level of serum I-FABP and positive rate of I-FABP of intestinal obstruction group was statistically higher than that of the control group （P^0.05） ;level of serum I-FABP and positive rate of I-FABP of ischemic group was statistically higher than that of the non-ischemic group （P~ 0.05）. ROC areas of I-FABP in discriminating intestinal ischemic in patients with acute intestinal obstruction was 0. 805 （95~CI： 0. 772--0. 938 ,P-~0.05）.. Conclusion I-FABP is potentially useful for discriminating intestinal ischemic in patients with acute in- testinal obstruction.
出处
《国际检验医学杂志》
CAS
2014年第4期410-411,共2页
International Journal of Laboratory Medicine
关键词
肠脂肪酸结合蛋白
肠梗阻
肠缺血
intestinal fatty acid binding protein
intestinal obstruction
intestinal ischemic
