摘要
目的观察并比较两种房水引流装置植入术降眼压的效果。方法选择健康新西兰白兔40只,单眼进行房水引流装置植入术。根据不同的植入物,分为NADI组和Ahmed组,每组20只实验兔。结果术后各组均未出现浅前房。NADI组术后8周眼压比术前下降19.4%;Ahmed组术后8周眼压下降幅度为15.7%。术后8周内,各组间眼压值统计对比,均有显著性差异(P<0.05),且NADI组的眼压值下降幅度要明显大于Ahmed组。结论 NADI组比Ahmed组的眼压值下降幅度大,且下降时间维持较长,表明此新型房水引流植入物NADI降眼压效果明显,具有很好的临床应用前景。
Objective To observe and compare the effects of intraocular pressure （IOP） drop on using two kinds of aqueous drainage device implantation. Methods Forty healthy New Zealand white rabbits were chosen for the experiments. According to different implant devices, they were divided into NADI （new aqueous drainage implant） group and Ahmed group respectively, with 20 rabbits in each. Results Neither group appeared shallow anterior chamber after operation. At 8th week after operation, the postoperative IOP of NADI group and Ahmed group was decreased by 19.4% and 15.7%, respectively, as compared to the preoperative IOP. Statistical comparison showed that there were significant differences in IOP between two groups within 8 weeks （P〈0.05）, and the IOP of NADI group was decreased more significantly than that of Ahmed group. Conclusions The IOP in NADI group was reduced more than that in Ahmed group, and such IOP drop was maintained for a longer period in NADI group, which means that NADI has an obvious IOP drop effect and good prospect in clinical application.
出处
《医用生物力学》
EI
CAS
CSCD
北大核心
2014年第1期66-71,共6页
Journal of Medical Biomechanics
基金
国家自然科学基金资助项目(31070840)
北京市属市管高等学校人才强教深化计划项目高层次人才项目(PHR201110506)
首都医科大学基础临床合作课题重点项目(12JL03)
关键词
青光眼引流装置
房水
引流
眼压
Glaucoma drainage devices（GDD）
Aqueous humor
Drainage
Intraocular pressure （IOP）
