摘要
目的探讨自动乳腺全容积成像技术(ABVS)对乳腺导管内乳头状瘤(IDP)的诊断价值。方法研究对象为2010年8月至12月在北京协和医院行乳腺病变切除活检的213例患者,共239个乳腺病变,均获得手术病理结果。以病理诊断为金标准,计算并比较ABVS和常规超声对IDP的诊断效力。结果 239个病变中,病理证实良性154个,恶性85个,其中IDP病变26个。ABVS共发现41个(17.2%)病灶符合IDP诊断标准,诊断敏感性、特异性、阳性预测值、阴性预测值、准确性分别为88.5%、91.5%、56.1%、98.5%、91.2%。常规超声共发现32个(13.4%)可疑IDP病灶,诊断敏感性、特异性、阳性预测值、阴性预测值、准确性分别为73.1%、93.9%、59.4%、96.6%、91.6%。结论 ABVS冠状面成像可以更好地显示乳腺导管结构,提高对IDP的诊断敏感性,为IDP的诊断及鉴别诊断提供更多信息。
Objective To investigate the value of automated breast volume scanning （ABVS） in the diagnosis of breast intraductal papilloma （IDP）. Methods Totally 239 lesions in 213 women who were sched- uled for open biopsy were investigated in this study. The patients underwent both ABVS and conventional ultra- sound （US）. According to the imaging diagnostic standards of IDP, the diagnostic accuracy for ABVS was cal- culated, and then compared with US, using histopathological examination as the gold standard. Results Among the 239 breast lesions studied, 85 were pathologically proved to be malignancies and 154 benign lesions, among which there were 26 cases of IDP. ABVS found 41 cases of IDP （ 17.2% ）, with the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy being 88.5%, 91.5%, 56. 1%, 98.5%, and 91.2%, respectively. In contrast, US found 32 cases of IDP （ 13.4% ）, with the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy being 73.1% , 93.9% , 59.4% , 96.6% , and 91.6%, respectively. Conclusion ABVS coronal images can better display the structures of dilated lactifer- ous ducts and the intraluminal echoes, increase the diagnostic accuracy of IDP, and thus provide more informa- tion for the diagnosis and differential diagnosis of IDP.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2014年第1期52-56,共5页
Acta Academiae Medicinae Sinicae
基金
高等学校博士学科点专项科研基金(20121106130002)~~
