摘要
目的探讨症状性颈内动脉系统狭窄或闭塞后侧支循环建立的危险因素。方法收集288例症状性颈内动脉系统重度狭窄或闭塞患者的临床资料,分析其危险因素。结果 166例患者出现侧支循环开放(侧支循环组),122例患者无侧支循环开放(无侧支循环组)。与无侧支循环组比较,侧支循环组高血压比率显著增高,收缩压显著降低(均P<0.05)。以侧支循环形成为因变量,采用Binary Logistic回归分析显示,高血压对不同病变部位狭窄或闭塞的侧支循环开放的差异无统计学意义(χ2=1.331,P=0.514);对初级、次级侧支循环建立的差异无统计学意义(χ2=0.306,P=0.580)。结论高血压对症状性颈内动脉系统重度狭窄或闭塞后侧支循环的建立有促进作用。
Objective To explore the risk factors of the establishment of collateral circulation with symptomatic carotid artery system stenosis or occlusion.Methods The clinical data of 288 patients with symptomatic carotid artery system severe stenosis or occlusion were collected,and the risk factors were analyzed.Results One hundred and sixty-six patients had collateral circulation （collateral circulation group）,and 122 patients had no collateral circulation （no collateral circulation group）.Compared with no collateral circulation group,the rate of hypertension in collateral circulation group was significantly increased,and systolic pressure was significantly decreased （all P 〈 0.05）.Binary Logistic regression analysis with collateral circulation as dependent variable revealed that there was no significant difference of hypertension among the different lesion segments with collateral circulation （x2 =1.331,P =0.514）,and there were no significant difference of hypertension between the primary and secondary collateral circulation （x2 =0.306,P =0.580）.Conclusion Hypertension may play a promotive role for the establishment of the collateral circulation with symptomatic carotid artery system stenosis or occlusion.
出处
《临床神经病学杂志》
CAS
北大核心
2014年第1期19-21,共3页
Journal of Clinical Neurology
基金
广西医疗卫生厅重点科研课题(重2011115)
关键词
颈内动脉系统
狭窄
闭塞
侧支循环
危险因素
carotid artery system, stenosis, occlusion
collateral circulation
risk factor
