摘要
目的:通过对唾液隐血与牙龈出血的相关性分析,探讨以唾液隐血测试(salivary occult blood test,SOBT)判断牙龈炎症状态的可行性。方法:对45例受试者的刺激和非刺激性唾液进行隐血测试,结合牙龈探诊出血(bleeding on probing,BOP)阳性位点百分比,以BOP%≥15%者作为慢性龈炎组,其余为牙龈健康对照组作关联分析,并对比患者牙周基础治疗前后的BOP%及SOBT变化,探讨SOBT与牙龈炎症的相关性,评估以SOBT检测牙龈炎症的灵敏度与特异度,应用SAS6.12软件包对数据进行统计学分析。结果:慢性龈炎组与牙龈健康对照组的刺激性SOBT有显著差异(P<0.01),非刺激SOBT有显著差异(P<0.05)。30例接受牙周基础治疗的慢性牙龈炎患者,BOP%显著下降(P<0.01),63%刺激性与90%非刺激性SOBT阳性者牙龈炎症得到改善,均有显著差异(P<0.01)。非刺激SOBT的灵敏度为32.35%,特异度为100%;刺激性SOBT的灵敏度为88.24%,特异度为81.82%。结论:SOBT与牙龈炎症存在一定关联性,可作为判断个体牙龈炎症及牙周疗效的客观依据,对在大规模人群中早期牙龈炎症的判定和筛检具有一定价值。
PURPOSE： To evaluate the reliability of salivary occult blood test （SOBT） for gingival inflammation. METHODS： Forty-five pre- and post-stimulation saliva samples were tested for occult blood, with bleeding on probing （BOP） as an indicator of gingival inflammation. Subjects with BOP%〈15% were defined as control group. The examinations were repeated 3 months after periodontal initial therapy. The relationship between the results of SOBT and gingival inflammation was analyzed. SAS6.12 software package was used for statistical analysis. RESULTS： The SOBT of pre- stimulation was higher in gingivitis group than in control group （P〈0.05）. BOP% and SOBT of post-therapy was significantly decreased （P〈0.01）, with 90% of pre- and 63% of post-stimulation SOBT turning negative. The sensitivity and specificity of pre- stimulation SOBT in screening gingivitis were 32.35% and 100%. The sensitivity and specificity of the post-stimulation SOBT were 88.24% and 81.82%. CONCLUSIONS： SOBT is correlated with gingival inflammation, which may be used as an objective parameter to evaluate gingival inflammation and the efficacy of periodontal therapy at individual level. It may offer a simple screening method for gingival inflammation applied in periodontal epidemiologic studies in large population.
出处
《上海口腔医学》
CAS
CSCD
北大核心
2014年第1期87-90,共4页
Shanghai Journal of Stomatology
关键词
隐血试验
牙龈炎症
唾液
流行病学
Occult blood test
Gingival inflammation
Salivary
Epidemiology
