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胃康灵颗粒治疗慢性胃炎210例临床观察 被引量:2

Observation on Wei-Kang-Ling Grain Treated 210 Cases with Chronic Gastritis
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摘要 目的:评价胃康灵颗粒临床治疗慢性胃炎肝胃不和瘀血阻络中医证候的疗效及安全性。方法:选择符合肝胃不和瘀血阻络中医证候的慢性胃炎患者280例,随机分为试验组210例和对照组70例,试验组予胃康灵颗粒及予胃苏颗粒模拟剂口服,对照组予胃苏颗粒及予胃康灵颗粒模拟剂口服,2组均以4 w为1个疗程,共有274例完成试验。通过对2组用药前后的疗效性指标和安全性指标的检测,综合评价胃康灵颗粒治疗慢性胃炎(肝胃不和瘀血阻络证)的有效性和安全性。结果:在中医证候疗效及各中医各单项症状疗效方面,试验组明显优于对照组,差异有统计学意义(P<0.05);2组受试者未见不良事件和不良反应发生,组间比较差异无统计学意义。结论:胃康灵颗粒治疗慢性胃炎肝胃不和瘀血阻络证疗效优于胃苏颗粒,安全性良好。 Objective: To investigate the clinical effect and safety of TCM Liver-Stomach Disharmony Syndrome and Blood Sta- sis Syndrome of chronic gastritis treated by the Wei-kang-ling grain. Methods: 240 patients with TCM Liver-Stomach Disharmony Syn- drome and Blood Stasis Syndrome Syndrome of chronic gastritis were randomly divided into two groups. Patients in treatment group ( n = 210) were treated by Wei-kang-ling grain and Wei-su grain Simulant. Patients in control group (n =70) were treated by Wei-su grain and Wei-kang-ling grain Simulant. The course of control test was 2 month, there were 274 patients completed the trial. Evaluate the clinical effect and safety of 2 groups by detecting the efficacy indicators and safety indicators of before and after treatment. Results: There was statistical significance between two groups on the clinical effect TCM Syndrome and each TCM individually symptom. The to- tal effective rate in treatment group was superior to that of control group ( P 〈 O. 05) . There was no evident adverse reaction in two groups and no statistical significance between two groups. Conclusion: The clinical effect of treating Liver-Stomach Disharmony Syn- drome and Blood Stasis Syndrome Syndrome of chronic gastritis with the Wei-kang-ling grain is superior to Wei-su grain. They have both good safety.
出处 《成都中医药大学学报》 2014年第1期63-65,共3页 Journal of Chengdu University of Traditional Chinese Medicine
基金 河北省中医药管理局2013年基金项目(编号:2013152)
关键词 胃康灵颗粒 慢性胃炎 中医证候 Wei-kang-ling grain Chronic gastritis TCM syndrome
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