摘要
目的 总结胃肠道间质瘤（gastrointestinal stromal tumor,GIST）的临床特征、诊断和治疗要点.方法 回顾性分析宁波市镇海第二医院45例GIST的临床资料.结果 45例中消化道出血25例,腹胀、腹痛20例,不完全肠梗阻7例,贫血22例;均行手术治疗,术后病理25例良性,13例交界性,7例恶性.均随访2～4年,3例肿瘤复发转移死亡,1例术后24个月复发行二次手术治疗.结论 GIST确诊有赖于病理检查,目前手术是最主要的治疗手段,分子靶向治疗有一定的辅助意义.
Objective To analyze the clinical features,diagnosis and treatment of gastrointestinal stromal tumors（GIST）.Methods The clinical data of 45 patients in Zhenhai Second Hospital of Ningbo were collected and analyzed retrospectively.Results Among the 45 cases,25 cases had gastrointestinal bleeding,20 cases had abdominal pain and bloating,7 cases had incomplete intestinal obstruction and 22 cases had anemia.All patients underwent surgery.According to postoperative pathology,25 cases were benign,13 cases were borderline,and 7 cases were malignant.Patients were followed up for 2 to 4 years.3 patients died of tumor recurrence and metastasis.one case recurred 24 months after surgery and underwent a secondary surgery.Conclusions The diagnosis of gastrointestinal stromal tumor depends on pathology.Surgery is currently the most important treatment.Molecular targeted therapy for gastrointestinal stromal tumor therapy has some secondary significance.
出处
《中华内分泌外科杂志》
CAS
2014年第1期62-63,共2页
Chinese Journal of Endocrine Surgery
关键词
胃肠道
间质瘤
诊断
治疗
Gastrointestinal tract
Stromal tumor
Diagnosis
Treatment
