摘要
目的：探讨该院2010～2012年真菌感染的动态变化及耐药情况，指导临床合理使用抗真菌药物。方法回顾性调查分析2010～2012年该院真菌病原菌分布和药敏试验情况，用WHONET5．6统计软件进行分析。结果3年来该院真菌感染病原菌主要为白色假丝酵母菌。分离标本主要是痰液和血液，内科、普外科和中西医结合科是真菌检出较多科室。5种假丝酵母菌对两性霉素B敏感率高，伊曲康唑耐药率较高。结论医院真菌感染病原菌分布发生变迁且真菌的耐药率不断升高，应加强真菌感染的动态监测和研究，减少肿瘤患者真菌感染的发生。
Objective To investigate the dynamic changes and drug resistance of fungal infection in our hospital during 2010 -2012 for guiding the clinical reasonable use of anti-fungal drugs .Methods The related clinical data and the drug sensitivity tests re-sults of fungal infection in the hospitalized patients from 2010 to 2012 were retrospectively analyzed by the WHONET 5 .6 soft-ware .Results Candida albicans was the major pathogen causing candida infection for these 3 years .The isolated specimens were mainly sputum and blood .In the departments of internal medicine ,general surgery and integrated Chinese and Western medicine ,the number of detected candida were more than that of the other departments .Five kinds of candida showed high sensitivity to ampho-tericin B and high resistance to itraconazole .Conclusion The distribution of pathogens causing nosocomial fungal infection has changed and the drug resistance rate is continuously rising .Therefore the dynamic monitoring and the study of fungal infection should be strengthened for reducing the occurrence of fungal infection in the patients with tumor .
出处
《国际检验医学杂志》
CAS
2014年第5期572-573,共2页
International Journal of Laboratory Medicine
关键词
真菌
微生物敏感性试验
抗药性
真菌
fungi
microbial sensitivity tests
drug resistance,fungal
