摘要
目的通过研究变温变压对高血压急诊就诊人次的影响．为制定高血压防护措施提供依据。方法采用基于时间序列的Poisson广义相加模型。控制时间的长期趋势、星期效应、节假日效应及其他对高血压疾病有影响的混杂因素，研究24h变温（△T）及24h变压（△P）与高血压急诊就诊人次的关系。结果降温大于5℃时老年人群（≥65岁）因高血压急诊就诊的危险度明显上升，且男性上升幅度较大；变压与高血压急诊就诊人次的关系呈U型曲线，变压幅度越大，患高血压就诊的危险度越高。其中老年男性对正变压最敏感，气压每升高1hPa老年男性高血压急诊就诊人次上升2．02％（95％CI：0．33～3．74，P〈O．05）；老年女性对降压反应更为敏感，气压每降低1hPa，其高血压急诊就诊人次增加2．27％（95％CI：0．78～3．78，P〈0．01）。结论温度和气压剧变，尤其是24h变压是诱发高血压及其相关疾病的危险因素。
Objective To provide the evidence for working out some measures to prevent and control hy- pertension by studying the effect of change in atmospheric temperature and pressure on the number of times to visit a doctor in an emergency for hypertension. Methods A time-series Poisson generalized additive model （GAM） was adopted to study the impact of 24 h atmospheric temperature change （AT）, and 24 h pressure change （Ap） on hy- pertension after controlling long time trend, week effect, holiday effect and other confounding factors including pol- lution factors and other meteorological variables. Results The relative risk （RR） of times to visit a doctor in old people （ ≥ 65 years old）, especially in male suffered from hypertension rose significantly when △T was decreased by more than 5 ℃. The relationship of RR and Ap was presented as a U-shaped curve. Old men were sensitive to posi- tive increase in Ap, when Ap increased by 1 hPa, their visiting times increased by 2.02 % （95 % CI： 0. 33 -3.74, P〈0.05 ） ;old women were more sensitive to decrease in Ap, a decrease in Ap by 1 hPa corresponding to 2.27% （95% CI： 0.78 -3.78） increase in visiting times （P〈0.01）. Conclusion Acute change in atmospheric tempera- ture and pressure, especially 24 h pressure change was the risk factor of hvDertension and other related diseases.
出处
《解放军预防医学杂志》
CAS
2014年第1期10-13,共4页
Journal of Preventive Medicine of Chinese People's Liberation Army
基金
国家公益性行业专项(No.GYHY201106034)
国家科技支撑计划(No.2012BAJ18B08)
国家科学和技术基础设施平台(No.2005DKA32403)
关键词
高血压
变温
变压
广义相加模型
hypertension
24-hour temperature change
24-hour pressure change
generalized additive model （GAM）
