摘要
目的分析胎儿宫内TORCH感染的超声表现特点,探讨超声检查对胎儿宫内感染的诊断价值,以期为提高胎儿宫内感染的诊断水平提供参考。方法对医院2010年3月-2013年3月收治的92名孕妇胎儿宫内先天性感染产前超声表现进行回顾性分析,对所有胎儿的资料进行调查,并对其结局进行随访,评价超声检查对胎儿宫内感染诊断的临床价值。结果 92例孕妇感染病原体依次为细菌、乙型肝炎病毒、巨细胞病毒、风疹病毒、支原体属、衣原体属、苍白密螺旋体、弓形虫、人类免疫缺陷病毒,分别占42.39%、26.09%、13.04%、5.43%、3.26%、1.09%、6.52%、1.09%、1.09%;92例产妇经确诊为宫内感染后3例经干预未能有效改善宫内感染状况而终止妊娠、6例家属要求终止妊娠、死胎及死产各1例,早产儿23例、低体质量儿16例、先天畸形儿1例、新生儿感染16例,其中1例HIV病毒感染、5例风疹病毒感染及10例巨细胞病毒感染,余25例均正常。结论超声检查可以检出胎儿宫内感染发生的一系列细微变化,可及时提示临床医师进一步进行病原学和病毒学检查,以确诊胎儿是否发生宫内感染,对孕妇及胎儿结局选择具有重要的临床意义。
OBJECTIVE To analyze the characteristics of the sonographic findings of TORCH infections of the fetuses and discuss the value of ultrasound examination in diagnosis of fetal intrauterine infections so as to improve the level of diagnosis of intrauterine infections. METHODS Totally 92 pregnant women with the fetuses with congenital intrauterine infections, who were treated in the hospital from Mar 2010 to Mar 2013, were enrolled in the study, then the prenatal sonographic findings of the subjects were retrospectively analyzed, the data of all the fetuses were investigated, the follow-up was conducted for the clinical outcomes, and the clinical value of ultrasound examination in diagnosis of fetal intrauterine infections was evaluated. RESULTS Of the 92 pregnant women, the pregnant women infected with bacteria accounted for 42.39 %, the cases of hepatitis B virus infection 26. 09%, the cases of cytomegalovirus infection 13.04%, the cases of rubella virus infection 5.43%, the cases of Mycoplasma infection 3.26 %, the cases of Chlamydia infection 1.09 %, the cases of Treponema pallidum infection 6.52%, the cases of toxoplasma infection 1.09%, the cases of human immunodeficiency virus infection 1. 09%. Of the 92 pregnant women with confirmed intrauterine infections, there were 3 cases who did not terminate the pregnancy due to ineffective interventions, 6 cases whose family members required to terminate the pregnancy, 1 case of fetal death, 1 case of stillbirth, 23 cases of preterm, 16 cases of low birth weight, 1 case of congenital malformation, and 16 cases of neonatal infections, including 1 case of HIV infection, 5 cases of rubella virus infection, and 16 cases of cytomega!ovirus infection; the rest of 25 cases were normal. CONCLUSION The ultrasound examination can detect a series of subtle changes of the fetal intrauterine infections, including that the clinicians should further perform the etiological and virological examination to determine whether the fetal intrauterine infections occurs, and it is of great significance to the selection of outcomes of both the pregnant women and the fetuses.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第6期1526-1527,1533,共3页
Chinese Journal of Nosocomiology
基金
南宁市卫生局重点支持基金项目(GN-2009B-041)
关键词
超声诊断
胎儿宫内感染
TORCH感染
Ultrasound diagnosis
Fetal intrauterine infection
TORCH infection
