摘要
目的 了解早期糖尿病肾病患者测定尿转铁蛋白的临床意义。方法 采用免疫散射比浊法测定82例无明显血管并发症的 NIDDM及 2 0 0名健康人尿转铁蛋白的排泄 (U TFE) ,将其与尿蛋白排泄 (U AE)进行比较。结果 无明显血管并发症的 NIDDM患者 UTFE增高的发生率明显高于 U AE增高的发生率 (5 1.2 %与2 8.0 % ,χ2 =9.31,P<0 .0 1) ,UTFE与 U AE呈明显正相关。结论 U TFE可能是一个较 UAE更敏感。
Objective To study the clinical significance of transferrin in earlier diabetic nephropathy.Method Using immunonephelometric assay urinary excretion of transferrin was measured in 200 healthy subjects and 82 non insulin dependent diabetes mellitus(NIDDM)subjects without obvious vascular complication.A comparison between UTFE(urinary transferrin excretion)and UAE(urinary albumin excretion)was made.Results In NIDDM the incidence of elevaed UTFE(51.2%)was significantly higher than that of UAE(28.0%),χ 2=9.31,P<0 01,UTFE correlated significantly with UAE.Conclusion UTFE might be a more sensitive and earlier marker for early recognition of renal complication of NIDDM.
出处
《山西医药杂志》
CAS
2001年第1期14-15,共2页
Shanxi Medical Journal
