摘要
目的分析糖尿病性神经病不同临床症状的神经电生理特点,探讨不同的神经电生理检测方法在早期诊断糖尿病性神经病中的价值。方法将糖尿病性神经病339例根据临床症状分为A组42例(自发疼痛、烧灼感),B组120例(肢体麻木、感觉异常),C组105例(易疲劳,四肢无力),D组72例(行走不稳)。分别进行周围神经运动神经传导速度(MNCV)及感觉神经传导速度(SNCV)、诱发电位波幅、远端潜伏期、肌电图、皮肤交感反应(SSR)、躯体感觉诱发电位(SEP)测定,并与本实验室相关检查项目年龄匹配的正常值进行比较。结果 339例患者中MNCV异常148例(43.7%),SNCV异常122例(36.0%),肌电图异常24例(7.1%),SSR异常41例(12.1%),SEP异常110例(32.4%)。与其他3组比较,A组SSR异常率最高(88.1%);C组MNCV异常率最高(94.3%);B组SNCV异常率最高(75.0%);D组SEP(下肢)异常率最高(86.1%),4组异常率比较,差异有统计学意义(P<0.05)。结论糖尿病性神经病早期联合应用几种不同的神经电生理检测技术,能提高早期诊断的阳性率,对无明显肌肉萎缩糖尿病的患者肌电图可不作为常规检测手段。
Objective To study the value of different electrophysiplogical methods in early diagnosis of diabetic neuropathy by analyzing the electrophysiological characteristics of diabetic neuropathy with different clinical manifestations.Methods Three hundred and thirty-nine diabetic neuropathy patients were divided into group A （n=42）,group B （n=120）,group C （n=105）,and group D （n=72）according to their clinical manifestations.Their MNCV,SNCV,AMP,LAT,EMG,SSR and SEP were assayed and compared with the age-matched normal values.Results Among the 339 patients,the MNCV,SNCV,EMG,SSR,and SEP were abnormal in 148 （43.7%）,122 （36.0%）,24 （7.1%）,41 （12.1%） and 110 （32.4%）,respectively.The SSR in group A was 88.1%,the MNCV ingroup C was 94.3%,the SNCV in group B was 75.0%,and the SEP in group D was 86.1%,which were significantly higher than those in the other 3 groups （P〈0.05）.Conclusion Different electrophysiplogical methods used in combination can improve the early diagnosis of diabetic neurophathy.EMG is not used as a routine diagnostic method in diabetic patients without severe muscle atrophy.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2014年第3期284-286,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
糖尿病
周围神经系统疾病
电生理学
糖尿病并发症
早期诊断
diabetes mellitus
peripheral nervous system diseases
electrophysiology
diabetes complications
early diagnosis
