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急性期深静脉血栓孕妇炎症因子的表达水平及与累及血管损伤程度的关系 被引量:8

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摘要 目的探索急性期深静脉血栓(DVT)孕妇炎症因子的表达水平与累及血管损伤程度的关联性。方法纳入符合要求的54例急性DVT妊娠女性作为观察组,择同期孕检正常的孕妇54例及正常人54例分别作为对照组。ELISA法测定所有入选病例IL-6、IL-8、IL-10及TNF-α浓度,并对观察组进行循环内皮细胞(CECs)计数检测和彩超量化评定。结果观察组各炎症因子的水平及CECs计数较正常人和正常孕妇均有明显升高,差异有统计学意义(P<0.05),除IL-10外其他炎症因子水平均与CECs的计数呈正相关,与超声评价呈等级相关(P<0.05)。结论炎症因子的表达水平与DVT急性期病变血管的损伤程度密切相关,可作为临床干预的可靠检测指标。
出处 《广东医学》 CAS CSCD 北大核心 2014年第4期558-560,共3页 Guangdong Medical Journal
基金 广东省佛山市医学类科技攻关项目(编号:201208275)
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