摘要
目的分析我院住院糖尿病患者泌尿道感染病原菌分类及耐药性情况,为临床经验性使用抗菌药物提供参考。方法回顾性分析2011年1月至2012年12月我院收治的217例糖尿病合并泌尿道感染患者,对其尿培养结果阳性的病原菌的分布及耐药性进行了统计分析。结果 217例住院糖尿病伴泌尿道感染患者中段尿标本中,检出病原菌237株,其中革兰阴性菌占73%,革兰阳性菌占21.1%,真菌占5.91%。其中单一菌株占90.78%,两种菌株占9.22%。革兰阴性菌对氨苄西林、复方磺胺、四环素等抗菌药物耐药率>60.0%,革兰阳性菌对青霉素、红霉素、四环素的耐药率>70.1%。结论住院糖尿病伴泌尿道感染患者尿标本中检出主要病原菌为革兰阴性杆菌,其中感染菌中大肠埃希菌居首位。
Objective To analyze the pathogen distribution and drug resistance of diabetes patients with urinary tract infection in our hospital,and to direct proper use of antibacterial drugs.Methods A retrospective analysis of the etiology specimens and susceptibility examination were used to analyze the urine specimen from the 217 cases of diabetes patients with urinary tract infection in hospital during January 2011 to December 2012.Results There were detec ted 237 of pathogens in the 217 cases of urinary tract infection with diabetes in hospitalized patients,which Gram-negative bacteria accounted for 73 %,Gram-positive bacteria accounted for 21.1 %,Fungi accounted for 5.91%,Single strain accounted for 90.78%,and both strains totally accounted for 9.22%.The resistance rate of Gram negative bacteria to ampicillin,sulfamethoxazole,tetracycline and other antimicrobial drug> 60.0%,and the resistance rate of Gram-positive bacteria to penicillin,erythromycin,tetracycline > 70.1%.Conclusion The urinary tract in fection pathogens in diabetes patients in hospital is mainly Gram-negative bacilli,and E.coli bacteria is dominant.
出处
《中国实验诊断学》
2014年第3期444-447,共4页
Chinese Journal of Laboratory Diagnosis
关键词
糖尿病
泌尿道感染
病原菌
耐药性
diabetes
urine tract infection
pathogens
drug resistance