摘要
目的探讨MRI动态增强扫描对宫颈癌的诊断价值。方法对经宫颈活检证实为宫颈癌的36例患者和15例健康志愿者行MRI常规及动态增强扫描,选取ROI绘制宫颈癌病灶及子宫正常组织的动态增强时间-信号曲线。测量相对信号增强率(RE、单位为%)和最大相对信号增强率(MRE、单位为%),以及最大信号增强率(ME、单位为%)及峰值时间(TP、单位为s)值。并进行统计学分析。结果宫颈癌病灶在动态增强扫描中明显强化,与周围正常组织对比明显。宫颈癌组宫颈病灶与子宫肌层测量的RE、MRE值有统计学差异(P<0.05)。正常宫颈组患者的宫颈-子宫肌层的差值与宫颈癌组的宫颈病灶-子宫肌层的差值比较中,其RE、MRE值差值比较也有明显统计学差异(P<0.05)。而各组比较的ME及TP无明显统计学差异(P>0.05)。结论 MR动态增强扫描能够反映宫颈癌组织的血供状态,准确评估肿瘤范围,有助于提高宫颈癌术前分期的准确性,指导临床治疗。
Objective To evaluate the diagnostic value of dynamic contrast-enhanced MR imaging in cervical cancer. Methods A total of 36 cases of pathologically conifrmed cervical cancer patients and 15 healthy volunteers with MRI data were analyzed. Time-intensity curves of ROI in pathological regions and normal regions were obtained and the enhancedrates at different times were calculated. The RE, MRE, ME and TP of various groups were compared with T-test. Results In dynamic contrast-enhanced scan cervical lesions signiifcantly enhanced, contrasting with the surrounding normal tissue. Cervical lesions and myometrium measured RE, MRE values were signiifcantly different （P〈0.05）, compared with the difference between the cervical and uterine myometrium in normal cervix group and the difference between cervical lesions and myometrium in cervical cancer groups, the RE, MRE value of the difference was statistically signiifcant compared also signiifcantly （P〈0.05）. Conclusions Dynamic contrast-enhanced MR imaging can relfect the blood supply of the tumor, accurate assessment of tumor extent, help to improve the accuracy of preoperative staging of cervical cancer and to guide clinical treatment.
出处
《中国医药指南》
2014年第7期3-4,共2页
Guide of China Medicine
基金
广州市科信局课题(项目编号:2012J4300076)
关键词
子宫
宫颈癌
磁共振成像
图像增强
Uters
Cervical cancer
Magnetic resonance imaging
Image enhancement
