摘要
引入微波技术,对以硫酸为催化剂,水浴回流分水制备苯甲酸乙酯的传统方法进行合理改进,重点考察微波功率、反应温度、反应时间对产率的影响.采用正交设计安排实验,实验结果经过优化组合,得出最佳反应条件为：辐射时间15 min,微波功率600 W,反应温度95℃.利用微波辐射加热方式替代普通的沸水浴合成苯甲酸乙酯,达到缩短反应时间,提高反应效率的目的,产物用减压蒸馏分离纯化,整个实验教学具有绿色化、现代化和综合化的特点,有利于提高学生实验兴趣,同时保证了在有限的实验时间内有充足的知识点和充分的技能训练.
The synthesis method of ethyl benzoate with sulfuric acid catalyst and oil-water separation was reasonably improved by using microwave irradiation instead of conventional water bath reflux. The effects of microwave power, reaction temperature and reaction time on the yield were emphatically investigated. The orthogonal experiment and optimal combination suggested the optimum reaction conditions： 15 min of irradiation time, 600 W of microwave power, and reaction temperature 95 ℃. The microwave radiation heating mode was used to replace the traditional boiling water bath method for the synthesis of ethyl benzoate for shortening the reaction time and improving the reaction efficiency. The vacuum distillation was applied to collect the pure product. With the characteristics of greening, modernization and comprehensiveness, the experiment increases the students＇ interest in experiment, and ensures adequate knowledge and skills for learning in the finite experimental time.
出处
《化学教育》
CAS
北大核心
2014年第6期35-38,共4页
Chinese Journal of Chemical Education
基金
湖南省教学改革基金资助项目(No.2012055)
关键词
微波合成
苯甲酸乙酯
实验改进
microwave synthesis
ethyl benzoate
experimental improvement
