摘要
目的观察穴位埋线联合西医治疗对慢性阻塞性肺疾病(COPD)患者远期疗效的影响。方法将90例COPD稳定期患者随机分为穴位埋线组(45例)和对照组(45例),穴位埋线组予以穴位埋线联合西医常规治疗,对照组予以西医常规治疗。观察两组治疗前后1年AECOPD次数,CAT评分,mMRC,肺功能(FEV1)的变化情况及安全性。结果治疗1年后完成随访87例COPD稳定期患者,其中穴位埋线组(44例)和对照组(43例)。治疗1年后,AECOPD发作次数≥1次的人数,穴位埋线组与对照组未显示出明显差异(P>0.05),但是穴位埋线组治疗1年后AECOPD发作次数≥1次的人数与治疗前比较明显减少(P<0.05);治疗1年后,穴位埋线组CAT评分和mMRC评分均较对照组治疗后明显改善(P<0.05);而肺功能(FEV1实测值)两组治疗前后均无明显改善(P>0.05)。两组患者血常规及肝、肾功能、尿常规等治疗前后均在正常范围内,穴位埋线组无局部组织不良反应及不适症状。结论穴位埋线联合西药治疗COPD稳定期患者能够提高患者生活质量,改善呼吸困难症状,远期疗效优于单纯西药治疗,但减少AECOPD次数的优势不明显,未能缓解患者肺功能恶化。
Objective：To observe the influence of long-term efficacy of thread-embedding at acupoint therapy combined western conventional therapy treating patients with chronic obstructive pulmonary disease （COPD）.Methods：90 cases of stable COPD patients were randomly divided into treatment group （45 cases）,which was used thread-embedding at acupoint therapy combined with western conventional therapy and control group （45 cases）,which was given the western conventional therapy only.There were some indices being recorded including the TCM symptoms,the frequency of severe AECOPD,COPD Assessment Test （CAT score）,Modified Medical Research Council Scale （mMRC）,and pulmonary function （FEV1） before and after treatment for 1 year.Results：After 1 year of treatment,87 completed follow-up cases of stable COPD patients among which thread-embedding at acupoint therapy group had 44 cases and control group had 43 cases.1 year after treatment,in terms of the number of AECOPD episodes ≥ 1 time,thread-embedding at acupoint therapy group and control group showed no significant difference （P＞ 0.05）.But the AECOPD episodes ≥ 1 time of therapy group was significantly reduced than before treatment after 1 year of treatment.The difference was statistically significant （P＜ 0.05）.The thread-embedding at acupoint therapy group was significantly improved than control group in CAT score and mMRC scores after 1 year of treatment.The difference was statistically significant （P＜ 0.05） which demonstrated the thread-embedding at acupoint therapy can improve quality of life and relieve dyspnea while pulmonary function （FEV1 measured value） before and after treatment was not improved （P＞ 0.05）.The thread-embedding at acupoint therapy group did not show the advantages of long-term efficacy.Routine blood count,liver and kidney function,routine urine tests,etc.of two groups of patients before and after treatment were within the normal range.The thread-embedding at acupoint therapy group had no adverse local tissue reactions and symptoms,thus was safe and reliable.Conclusion：Thread-embedding at acupoint therapy combined with western conventional therapy can improve quality of life and improve dyspnea of patients with stable COPD.Long-term efficacy is superior to using western medicine alone.Although the therapy fails to obviously reduce the number of AECOPD or alleviate the deterioration of pulmonary function.
出处
《中国中医急症》
2014年第3期416-419,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
上海市卫生局科研基金项目(2010216)
