切口浸润硫酸镁复合布比卡因对腹腔镜胆囊切除术后剑突下切口疼痛的影响被引量：1

下载PDF

导出

摘要目的探讨切口浸润硫酸镁复合布比卡因对腹腔镜胆囊切除术(LC)后剑突下切口疼痛的镇痛效果。方法 40例择期行LC患者随机分为两组:B组与BM组。B组为布比卡因组:0.75%布比卡因5 ml+生理盐水至15 ml;BM组为硫酸镁+布比卡因组:0.75%布比卡因5 ml+25%硫酸镁1 ml+生理盐水至15 ml。手术结束后即刻,沿剑突下切口分别皮下浸润2 ml,全层浸润3 ml,总量5 ml。记录患者术后1 h、2 h、4 h、8 h、24 h时静态以及动态视觉模拟评分(VAS),所有患者术后均不用镇痛药。结果 BM组的静态VAS评分在术后4h内显著小于B组(P<0.05),BM组的动态VAS评分在术后24h内显著小于B组(P<0.05)。结论切口浸润硫酸镁与布比卡因的混合液可以显著减少LC后剑突下切口疼痛。

作者郑永锋邵东华

机构地区江苏大学附属人民医院麻醉科

出处《齐齐哈尔医学院学报》 2014年第4期499-500,共2页 Journal of Qiqihar Medical University

关键词硫酸镁布比卡因切口浸润腹腔镜胆囊切除术

分类号 R657.41 [医药卫生—外科学]

引文网络
相关文献

参考文献5

1Joris J,Thiry E,Paris P,et al.Pain after laparoscopic cholecystectomy:characteristics and effect of intraperitoneal bupivacaine[J].Anesth Analg,1995,81:379-384.
2Lee IO,Kim SH,Kong MH,et al.Pain after laparoscopic cholecystectomy:The effect and timing of incisional and intraperitoneal bupivacaine[J].Can J Anaesth,2001,48:545-550.
3吴进,汪正平,颜涛,彭中美,李士通.布比卡因局部浸润对腹腔镜胆囊切除术后切口疼痛的影响[J].临床麻醉学杂志,2010,26(1):30-32. 被引量：14
4Tauzin-Fin P,Sesay M,Svartz L,et al.Wound infiltration with magnesium sulphate and ropivacaine mixture reduces postoperative tramadol requirements after radical prostatectomy[J].Acta Anaesthesiol Scand,2009,53:464-469.
5徐妍君,张俊杰,汪正平.镁离子辅助镇痛作用研究进展[J].中华医学杂志,2011,91(10):717-719. 被引量：5

二级参考文献41

1温丽婷,许兵,孙军霞.局部注射布比卡因对腹腔镜术后镇痛的研究[J].现代护理,2005,11(19):1581-1582. 被引量：1
2Ure BM, Troidl H, Spangenberger W, et al. Pain after laparoscopic eholecystectomy. Intensity and localization of pain and analysis of predictors in preoperative symptoms and intraoperative events. Surg Endosc, 1994,8: 90-96.
3Joris J, Thiry E, Paris P, et al. Pain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine. Anesth Analg, 1995,81 : 379-384.
4Lee IO, Kim SH, Kong MH, et al. Pain after laparoseopie cholecystectomy: the effect and timing of ineisional and intraperitoneal bupivacaine. Can J Anaesth,2001,48: 545-550.
5Bisgaard T, Klarskov B, Kristiansen VB, et al. Multi-regional local anesthetic infihration during laparoseopic eholeeysteetomy in patients receiving prophylactic multi-modal analgesia: a randomized, double-blinded, placebo-controlled study. Anesth Analg, 1999,89.. 1017 1024.
6Sarac AM, Aktan AO, Baykan N, et al. The effect and timing of local anesthesia in laparoscopic cholecystectomy. Surg Laparose Endosc, 1996,6 : 362-366.
7Lysakowski C, Dumont L, Czarnetzki C, et al. Magnesium as an adjuvant to postoperative analgesia: a systematic review of randomized trials. Anesth Analg, 2007, 104: 1532-1539.
8Gupta K, Vohra V, Sood J. The role of magnesium as an adjuvant during general anaesthesia. Anaesthesia, 2006,61 : 1058-1063.
9Jee D, Lee D, Yun S, et al. Magnesium sulphate attenuates arterial pressure increase during laparoscopic cholecystectomy. Br J Anaesth. 2009. 103: 484-489.
10Tauzin-Fin P, Sesay M, Delort-Laval S, et al. Intravenous magnesium sulphate decreases postoperative tramadol requirement after radical prostatectomy. Eur J Anaesthesiol, 2006, 23: 1055- 1059.