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TCT及HPV检查对宫颈疾病筛查价值的Meta分析研究 被引量:29

The Role of TCT and HPV Detection in Cervical Cancer Screening:a Meta Analysis
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摘要 [目的]应用Meta分析的方法对HPV检查、液基细胞学检查(TCT)及两种检查方法联合应用对宫颈疾病的筛查价值进行研究。[方法]通过CNKI、万方、维普、PUBMED及MEDLINE数据库检索2003年至2013年3月的文献,根据文献纳入标准进行文献筛选,利用Review Manager5.0软件对各组数据进行Meta分析,比较HPV检查、TCT检查以及两种方法联合应用对宫颈疾病的筛查价值。[结果]共筛选出19篇符合标准的文献。TCT检查对宫颈疾病的筛查价值优于HPV检查(OR 0.56,95%CI:0.49~0.63,P〈0.00001)。两种方法联合应用对于宫颈疾病的筛查价值均优于单独使用HPV或者TCT检查(OR 0.26,95%CI:0.08~0.70,P〈0.00001;OR 0.49,95%CI:0.16~1.47,P〈0.00001)。[结论]TCT与HPV检查方法联合,对宫颈疾病诊断效能高于两种检查方法单独使用。 [Purpose] To compare the value of HPV test,liquid-based cytologic test(TCT) and combination of the two methods in screening cervical disease. [Method] Literatures in CNKI,Wanfang,VIP database,PUBMED and MEDLINE from 2003 to March 2013 were retrieved according to strict selection standard. Meta analysis was made by Review Manager5.0 software to compare the value of HPV test,TCT test and combination of the two methods in screening of cervical disease. [Results] Nighteen studies were included. TCT test was superior to HPV examination in cervical disease screening(OR0.56,95%CI:0.49~0.63,P<0.00001). Combination of the two methods for cervical disease screening is superior to HPV or TCT alone(OR 0.26,95%CI:0.08~0.70,P<0.00001;OR 0.49,95%CI:0.16~1.47,P<0.00001). [Conclusion] Combination of HPV test and TCT test reveals higher efficiency than either of them in cervical disease screening.
出处 《肿瘤学杂志》 CAS 2014年第3期203-207,共5页 Journal of Chinese Oncology
基金 吉林大学教学改革资助项目 吉林省教育厅资助项目
关键词 宫颈疾病 筛查 诊断 人乳头状瘤病毒 液基细胞学检查 cervical disease screening diagnosis human papillomavirus liquid-based cytologic test
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参考文献4

  • 1Cao ZY.Chinese obstetrics and gynecology [M] .2nd ed. Beijing : People' s Medical Publishing House,2004. 1848-1852,2012-2028.
  • 2Lu ZH, Deng YJ. Review on common screening technique for cervical cancer [J]. Laboratory Medicine and Clinic, 2011,8(2):206-208.
  • 3Li P,Xu Y,Hang GQ,et al. Diagnostic value of TCT combined with high-risk type HPV DNA detection in cer- vical disease screening[J].Intemational Journal of Labora- tory Medicine, 2012,33 (9) : 1123-1125.
  • 4Tang LP,Tan MZ. Application of HPV and LCT tests in cervical cancer screening [J].Chinese Journal of Modern Drug Application,2009,3 (6):86-87.

同被引文献173

  • 1王智宇,包生武,张洪炜,杨波,张燕.血清人绒毛膜促性腺激素β亚基、孕酮、肌酸激酶及肌酸激酶/孕酮在早期异位妊娠的诊断价值[J].宁夏医学杂志,2012,34(8):723-725. 被引量:3
  • 2王静,绉吟.宫颈刮片、阴道镜及HPV检测在诊断宫颈癌和癌前病变中的应用[J].中国临床医学,2005,12(1):118-119. 被引量:12
  • 3蔡娱飞,朱光泽.高危型人乳头瘤病毒DNA检测在宫颈癌筛查中的作用[J].中国妇幼保健,2006,21(24):3434-3436. 被引量:28
  • 4谢幸,苟文丽.妇产科学[M].第8版.北京:人民卫生出版社,2013:258-264.
  • 5Whitlock EP, Vesco KK, Eder M, et al.Liquid-based cytology and human papillomavirus testing to screen for cervical cancer:a systematic review for the u.s.Preventive services task force[J ].Am Intern Med, 2011,155(10) : 687-697.
  • 6Juric D,Mahovlicv V,Rajhvajn S,et al.Liquid-based cy- tology-new possibilities in the diagnosis of cervical lesions [ J ] .Coil Antropol, 2010,34( 1 ) : 19-24.
  • 7Saslow D,Solomom D,Lawson HW,et al.Ameirican Cancer Society,American Society for Colposcopy and Cervical Pathology,and American Society for Clinical Pathology screening guidelines for the prevention ang early detection of cervical cancer[ J ].Am J Clin Pathol, 2012, 137 (4) : 516- 542.
  • 8Wu R, Belinson SE, Du H, et al.Human papillomavirus me- ssenger RNA assay for cervical cancer screening:the Shenzhen Cervical Cancer ScreeningTrial [J ].Int J Gynccol Cancer, 2012,20( 8 ) : 1411-1414.
  • 9Dxion EP,King LM,adams MD,et al.Isolantion of RNA from residual BD surepath liquid-based cytology specimens and detection of HPV E6/E7 MRNA using the pretectt HPV-proofer assay [ J ].J Virol Methods, 2008,154 ( 1-2 ) : 220-222.
  • 10Hausen H. Papillomaviruses in the causation of human cancers-a brief historical account[J]. Virol, 2009,384 (2):260 -265.

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