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脐血来源细胞因子诱导杀伤细胞的研究进展 被引量:1

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摘要 Schmidt—Wolf等于1991年首次报道了具有高增殖能力和高细胞毒性的细胞因子诱导的杀伤细胞(cytokine—inducedkillercells,CIK细胞)。CIK细胞是一种极具临床应用前景的过继性细胞免疫治疗(adoptivecellularimmunotherapy,ACI)的效应细胞。CIK细胞中起杀伤作用的主要效应细胞同时表达CD3和CD56两种膜蛋白分子,兼具有T淋巴细胞强大的抗肿瘤活性和自然杀伤细胞(NK细胞)主要组织相容性复合体(MHC)非限制性杀瘤的特点。
出处 《中华医学杂志》 CAS CSCD 北大核心 2014年第10期790-792,共3页 National Medical Journal of China
基金 卫生部新生儿疾病重点实验室开放课题(2012) 河南省省级大学生创新创业训练计划(2013sjxm034)
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