摘要
目的 探讨输血前进行不规则抗体检验的临床意义和实际应用价值.方法 对2500例输血患者进行输血前不规则抗体检验.结果 2 500例输血前不规则抗体检查中,出现有15例患者血清中含有不规则抗体,阳性率为0.60％;其中男性0.12％ （3/2 500）、女性0.48％（12/2 500）,女性不规则抗体阳性率明显的高于男性不规则抗体阳性率（x2=7.34,P＜0.05）;主要表现为抗C、抗D、抗E和抗M类型以及非特异性抗体,所占的比例分别为：13.3％、26.7％、20.0％、33.3％、6.7％.不规则抗体阳性输血者输血超敏反应发生率为100.0％,不规则抗体阴性输血者输血超敏反应发生率为0.0％,两组差异有统计学意义（x2=9.28,P ＜0.05）.结论 输血前对患者进行不规则抗体检验能够有效的指导患者进行正确的输血,并能够有效的预防和降低输血超敏反应,确保患者输血过程中的安全.
Objective To investigate the clinical significance and application value of the irregular antibody test before transfusion. Methods The irregular antibody test was conducted in 2 500 patients before blood transfusion. Results Through the analysis of irregular antibody examination of 2 500 patients with blood transfusion, 15 cases appeared irregular antibodies in the serum, the positive rate was 0.60%. The positive rate of male irregular antibody was 0.12% （3/2 500）,the positive rate of female irregular antibody was O. 48% （12/2 500）. The positive rate of female irregular antibody was significantly higher than that of male irregular antibody （X2 = 7.34,P 〈 0.05 ） ; The irregular an- tibodies were mainly anti C,anti D,anti E and anti M type and non-specific antibody,the proportions were 13.3%, 26. 7% ,20.0% ,33.3% ,6.7%. The incidence rate of blood transfusion hypersensitivity reactions in irregular antibody positive donor was 100.0%, that in irregular antibody negative patients was 0.0%, the difference between the two groups was statistically significant （X2 = 9.28 ,P 〈 0.05）. Conclusion Irregular antibody test in patients before blood transfusion can effectively guide the patients to correct blood transfusion, and can effectively prevent and reduce blood transfusion hypersensitivity, improve the safety in the process of blood transfusion.
出处
《中国基层医药》
CAS
2014年第6期842-843,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
输血
不规则抗体
Blood transfusion
Irregular antibody
