摘要
目的 探讨醋酸白（visual inspection with acetic acid,VIA）及碘试验（visual inspection with Lugol iodine,VILI）在宫颈上皮内瘤变（ceivical intraepithelial neoplasia,CIN）早期筛查中的临床意义.方法 利用醋酸白及碘试验方法对中越边境广西凭祥、龙州、宁明、大新等县妇幼保健院、县医院及广西壮族自治区民族医院门诊患者共2 016例行宫颈病变筛查,VIA/VILI阳性者及阴性但临床反复接触性出血、白带增多等可疑宫颈病变者行阴道镜检查并活检,以病理学诊断为金标准,CINⅠ以上为阳性病例.结果 2 016例中VIA/VILI检出阳性率从7.08%~17.95%不等,各地区检出阳性率中民族医院和大新县妇幼保健院检出阳性率低于宁明县妇幼保健院（P〈0.05）;2 016例VIA/VILI检查诊断CIN的灵敏度为69.77%、特异度为91.94%,高度病变（CINⅡ以上）筛查的灵敏度为71.21%、特异度为90.00%.结论 VIA/VILI在CIN早期筛查中实用性强,提高VIA/VILI图像的识别水平及阴道镜技术,可提高CIN尤其是高级别CIN诊断的准确率,降低漏诊率.
Objective To evaluate the visual inspection with acetic acid（VIA）/visual inspection with Lugol iodine（VILI） in the early screening of cervical intraepithelial neoplasia（CIN）.Methods 2013,2 016 women were screened by VIA/VILI for the early CIN in women and children＇s health care hospital or county hospital in Pingxiang, Longzhou,Ningming, Daxin county nearby Vietnam, as well as Guangxi National Hospital.The patients whose VIA/VILI were positive or negative but suspicious in clinics were done colposcopy and biopsy,pathological diagnosis of biopsy as the gold standard, CINⅠ and over were positive cases.Results A total of 2 016 women were brought into the test, positive detection range of VIA/VILI was from 7.08%-17.95%,the positive rates of Guangxi National Hospital and Daxin Hosiptal were under the positive rate of Ningming Hospital in different regions（ P〈0.05）;Sensitivity and specificity of VIA/VILI for CIN were 69.77% and 91.94%, respectively, 71.21% and 90.00% respectively for high grade CIN. Conclusion VIA/VILI shows practicality in the early screening of CIN, improving the skill of image recognition and colposcopy would approve the accuracy and reduce misdiagnosis rate.
出处
《河北医科大学学报》
CAS
2014年第3期272-275,共4页
Journal of Hebei Medical University
关键词
宫颈上皮内瘤样病变
多相筛查
病理学
临床
cervical intraepithelial neoplasia
multiphasic screening
pathology,clinical
