摘要
目的探讨军人隆起型糜烂性胃炎(EGP)与幽门螺杆菌(Hp)感染及消化性溃疡(PU)的关系。方法以我院2008年1月—2013年1月间收治的128例南方某部队军人EGP患者为研究对象,行胃镜和组织活检,用碳-13(13C)呼气快速尿素酶试验和组织染色法检测Hp感染,病理学分析胃黏膜炎性反应、固有腺体萎缩和肠上皮化生情况。结果南方某部军人EGP患者的Hp感染率为67.2%(86/128)。EGP伴PU的发生率为46.1%(59/128),伴PU的EGP患者的Hp感染率(81.4%)显著高于不伴PU的EGP患者的Hp感染率(55.1%,P<0.01)。胃窦病变组的Hp感染率(70.6%)明显高于胃体病变组的Hp感染率(47.4%,P<0.01)。伴PU的EGP患者的活动性炎症、腺体萎缩和肠上皮化生的发生率均明显高于不伴PU的EGP患者的发生率(均P<0.05)。结论 Hp感染与军人EGP伴PU的发病与进展有关。
Objective To discuss the relationship between erosive gastritis protuberance （EGP） complicated with peptic ulcer （PU） and helieobacter pylori （Hp） infection in a southern army. Methods A total of 128 southern army patients diagnosed as ECP in our hospital from January 2008 to January 2013 were enrolled in the study. All the patients underwent gastroseopy and biopsy. The existence of Hp infection was detected with J3C-urea breath test and staining, and then the gastric mucosal inflammation, atro- phy and intestinal metaplasia were analyzed by pathological determination. Results The Hp infective rate of EGP was 67.2% （86/128） in the southern army. The incidence rate of EGP with PU was 46. 1% （59/128）. Hp infective rate was significantly higher in the EGP patients with PU than in those without PU （81.4% vs 55.1% , P 〈 0.05 ）. Hp infective rate of gastric antrum lesions （70.6%） was significantly higher than that of gastric body lesions （47.4% , P 〈 0.01 ）. The incidences of active gastric mucosal inflammation, glandular epithelial atrophy and intestinal metaplasia in EGP with PU were significantly higher than that in EGP without PU （ P 〈 0.05 ）. Conclusion Hp infection may be associated with the occurrence and the development of EGP com- plicated with PU in the southern army.
出处
《临床军医杂志》
CAS
2014年第3期227-229,共3页
Clinical Journal of Medical Officers
关键词
隆起型糜烂性胃炎
幽门螺杆菌
消化性溃疡
病理变化
erosive gastritis protuberance
helicobacter pylori
peptic ulcer
pathological change
