摘要
目的:观察米非司酮治疗围绝经期患者子宫内膜异位症(EMT)的临床疗效。方法:将平顶山市第二人民医院2010年2月至2012年7月确诊为围绝经EMT患者50例,随机分为对照组及观察组,每组25例,对照组患者给予孕三烯酮治疗,观察组患者给予米非司酮治疗。比较两组患者子宫内膜异位症临床疗效、不良反应及治疗前后血清CA-125含量。结果:观察组患者子宫内膜异位症的治疗有效率明显高于对照组(P<0.05);观察组不良反应发生率明显低于对照组(P<0.05);治疗后观察组的CA-125含量明显低于对照组(P<0.05)。结论:米非司酮治疗围绝经期患者EMT的临床疗效好于孕三烯酮的治疗。
ObjectiveTo observe clinical effects of mifepristone in treatment of endometriosis （EMT） for perimenopausal pa-tients. Methods：50 perimenopausal patients with EMT in Pingdingshan 2nd people＇s hospital from Feb. 2010 to Jun. 2012 were ran-domly divided into control group （25 cases） and observation group （25 cases）. The cases in control group were treated by gestrinonewhile those in observation group were treated with mifepristone. The clinical effects, adverse reactions and serum CA-125 contents be-fore and after the treatment of the two groups were compared. Results： The effective rate of observation group was obviously higher thanthat of control group, and the difference between the two groups had the statistical significance （P〈0. 05）. The incidence rate of theadverse reactions of observation group was obviously lower than that of control group, and the difference between the two groups had thestatistical significance （P〈0. 05）. After the treatment, the CA-125 content of observation group was obviously lower than that of con-trol group （P〈0. 05）. Conclusions： The curative effect of mifepristone in the treatment of EMT for the perimenopausal patients is bet-ter than that of gestrinone.
出处
《中国民康医学》
2014年第2期38-39,共2页
Medical Journal of Chinese People’s Health
关键词
米非司酮
围绝经期
EMT
Mifepristone
Perimenopause
