摘要
近年的研究显示,我国H3、H4、H6、H9亚型等低致病性禽流感病毒的分离呈现上升的趋势,说明低致病性禽流感的感染越来越严重。从低致病性禽流感病毒分离株基因序列的研究来看,多种LP-AIV毒株之间发生了基因交换,尤其是内部基因之间的交换。同时也出现HP-AIV H5、H7亚型毒株与LP-AIV H9、H6亚型内部基因的交换,从而产生了危害更大的新毒株。2013年的H7N9亚型禽流感病毒片段重配研究结果显示,有6个基因片段源于H9N2亚型禽流感病毒,提示低致病性禽流感的危害越来越严重。
Recent studies showed that the isolates of H3, H4, H6 and H9 low pathogenic avian influenza viruses（LPAIV） were showing a rising trend,indicating that the infection of LPAIV was more serious in china. According to gene sequence studies of LPAIV, genetic exchanges appeared between multiple LPAIV, especially between the internal genes. Simultaneously,the internal genetic exchanges between HPAIV（such as HS,H7 strains） and LPAIV（such as H9, H6 strains） occurred,which resulted in producing more dangerous new strains. HTN9 avian influenza virus happened in china in 2013, and the study showed that six gene segments were from H9N2 avian influenza virus, suggesting that the harm of LPAIV was more serious.
出处
《动物医学进展》
CSCD
北大核心
2014年第4期121-124,共4页
Progress In Veterinary Medicine
关键词
低致病性禽流感
遗传进化
致病性
low pathogenic avian influenza
genetic evolution
pathogenicity
