摘要
目的探讨早期静脉注射人免疫球蛋白治疗重症手足口病的临床效果。方法将62例重症手足口病患儿分为治疗组(n=31)和对照组(n=31),给予抗炎、抗病毒、退热等常规治疗,治疗组在常规治疗的基础上早期静脉注射人免疫球蛋白,观察两组的临床疗效及精神症状改善、体温消退、食欲改善情况及平均住院时间。结果治疗组显效率及总有效率明显高于对照组(P<0.05);治疗组的体温消退时间、食欲改善时间、精神症状消失时间、平均住院时间明显短于对照组,两组差异有统计学意义(P<0.05)。结论早期静脉注射人免疫球蛋白能明显改善重症手足口病患儿的症状,临床疗效显著,且通过早期积极干预可缩短病程、减轻症状、缩短住院时间。
Objective To explore the clinical curative effect of early intravenous injection human immunoglobulin in treatment of severe hand foot mouth disease. Methods 62 cases of patients with severe hand foot mouth disease were divided into treatment group （n=31） and control group （n=31）,all were given with anti-inflammatory,antiviral,antipyretic and other conventional treatment,the treatment group patients were given early intravenous immunoglobulin therapy on the basis of conventional,and the clinical curative effect of two groups and mental symptoms,fever subsided,the appetite to improve the situation and the average length of stay were observed. Results The markedly effective rate and total ef- fective rate of the treatment group was significantly higher than that of the control group respectively （P〈0.05）.The time of body temperature,appetite improved time,psychiatric symptom disappearance time,the average hospitalization time of the treatment group was shorter than that of the control group respectively,the two groups had significant difference （P〈 0.05）. Conclusion Early human immunoglobulin for intravenous injection can obviously improve the symptoms of chil- dren with severe hand foot and mouth disease, the clinical curative effect is remarkable,and by early active intervention can shorten the course,reduce symptoms,shorten the hospitalization days.
出处
《中国当代医药》
2014年第9期64-65,共2页
China Modern Medicine
基金
广东省肇庆市科技创新计划项目(2013E146)
关键词
手足口病
免疫球蛋白
退热
Hand foot and mouth disease
Immunoglobulin
Subsided fever
