摘要
目的观察肠内营养(EN)与肠外营养(PN)治疗重症急性胰腺炎(SAP)的临床效果。方法将64例SAP患者随机分为EN组和PN组,每组各32例。两组均给予常规治疗,PN组采用肠外营养治疗,EN组采用肠内营养治疗。分别在入院时及治疗14 d后采血测定C-反应蛋白(CRP)及相关生化指标,观察两组患者感染并发症、手术治疗率、住院时间及死亡率。结果治疗14 d后,两组患者的CRP及生化指标均较治疗前明显改善(P<0.01);与PN组比较,EN组治疗后血清白蛋白明显升高(P<0.01),而丙氨酸氨基转移酶明显降低(P<0.01),其他指标比较差异无统计学意义(P>0.05)。EN组感染率低于对照组(P<0.05),住院时间短于对照组(P<0.01),但两组手术治疗率及死亡率比较,差异无统计学意义(P>0.05)。结论与PN治疗SAP相比,EN在改善患者营养状况、减少并发症和缩短住院时间等方面更有优势。
Objective To compare the clinical effect of enteral nutrition （EN） and parenteral nutrition （PN） in the treat- ment of severe acute pancreatitis （SAP）. Methods 64 patients with SAP were randomly divided into EN group and PN group with each group of 32 cases,both group receiving conventional treatment,moreover,the PN group was given par- enteral nutrition,while the EN group was given enteral nutrition for 14 days.The C-reactive protein （CRP） and relative biochemical criterion were detected at admission and the fourteenth day after treatment.The infective complications,op- eration rate,hospital stays and mortality rate were observed at the same time. Results CRP and relative biochemical criterion were improved obviously in both groups after treatment （P〈0.01）.Compared with PN group,the EN group had higher serum albumin,lower ALT after treatment （P〈0.01）, but there were not significant differences in other index be- tween both groups （P〉0.05）.The infection rate and hospital stays in EN group were lower than those in PN group （P〈 0.05 or P〈0.01）,but there were not significant differences in operation rate and mortality rate between both groups （P〉 0.05）. Conclusion Compare with PN support in the treatment of SAP,EN support shows advantages on melioration of nutrition,reduction of complications and shortening of hospital stays.
出处
《中国当代医药》
2014年第10期21-23,共3页
China Modern Medicine
基金
广东省东莞市科技计划项目(201110515000570)
关键词
重症急性胰腺炎
肠内营养
肠外营养
Severe acute pancreatitis
Enteral nutrition
Parenteral nutrition
