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内科主导的代谢手术治疗糖尿病的初步实践 被引量：7

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摘要 肥胖症和2型糖尿病的流行已成为全球性公共卫生面临的重大挑战,2型糖尿病合并肥胖使其治疗更具挑战.近三十年来,临床实践显示肥胖合并糖尿病患者在接受减重手术后除体重下降外,糖尿病病情亦得到显著改善,大多无需用药即能有效地控制血糖在正常范围,疗效明显优于常规内科治疗[1-3],且伴随的代谢综合征和高血压等相关合并症也得到明显缓解[4],甚至有报道这类患者的肿瘤发生率也显著降低[5].糖尿病减重手术治疗的有效性已得到临床的充分认可,近年来多个专业学会先后发表声明、专家共识或指南将减重手术列为合并病态性肥胖的糖尿病患者的治疗方式[6-8].
作者 陈静 祝之明
机构地区 第三军医大学大坪医院野战外科研究所高血压内分泌科全军高血压代谢中心重庆市高血压研究所
出处 《中华糖尿病杂志》 CAS CSCD 2014年第3期148-151,共4页 CHINESE JOURNAL OF DIABETES MELLITUS
基金 国家自然科学基金（81370353） 国家重点基础研究发展计划（973计划,2012CB517800） 重庆市科委国际科技合作基金科技平台与基地建设项目（CSTC2011gjhz0002）
关键词 2型糖尿病 代谢综合征 手术治疗 内科治疗 临床实践 合并糖尿病 相关合并症 肿瘤发生率
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献22

  • 1Geltrude M, Simona P, Andrea DG, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes [ J ]. N Engl J Med, 2012, 366:1577-1585.
  • 2Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta- analysis[ J：. Am J Med, 2009,122: 248-256.
  • 3Schauer PR, Kashyap SR, Wolski K, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes [J]. NEnglJMed,2012,366:1567-1576.
  • 4. Gloy VL, Briel M, Bhatt DL, et al. Bariatric surgery versus non- surgical treatment for obesity: a systematic review and meta- analysis of randomised controlled trials [ J ]. BMJ, 2013, 347 : 15934.
  • 5Sjtistr：m L, Gummesson A, Sj：str：m CD, et al. Effects of bariatric surgery on cancer incidence in obese patients in Sweden. (Swedish Obese Subjects Study ): a prospective, controlled intervention trial[ J：. Lancet Oneol, 2009,10:653-662.
  • 6Mechanick JI, Kushner RF, Sugerman HI, et al. American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Smgery Medical Guidelines for Clinical Practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient [ J]. Surg Ohes Relat Dis, 2008,4(5 Suppl) :S109-184.
  • 7Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/ TOS guideline for the management of overweight and obesity in adults: A report of the American College of Cardiology/American Heart Association Taskforce on Practice Guidelines and The Obesity Society[J]. Circulation, 2013 Nov 12. [ Epub ahead of print ].
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  • 9Lomamto D, Lee W J, Goel R, et al. Bariatric surgery in Asia in the last 5 years ( 2005-2009 ) [ J 1- Obes Surg, 2012,22 : 502- 506.
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二级参考文献119

  • 1祝之明.代谢性高血压:一个值得探索的问题[J].中华高血压杂志,2006,14(11):859-860. 被引量：37
  • 2Yang W, Lu J, Wang J, et al. Prevalence of diabetes among men and women in china [J]. N Engl J Med, 2010, 362 (12): 1090-1101.
  • 3Rubino F, Kaplan LM, Schauer PR, et al. The Diabetes Surgery Summit Consensus Conference: Recommendations for the evaluation and use of gastrointestinal surgery to treat type 2 diabetes mellitus [J]. Ann Surg, 2010, 251(3): 399-405.
  • 4Ferchak CV, Meneghini LF. Obesity, bariatric surgery and type 2 diabetes- a systematic review [J]. Diabetes Metab Res Rev, 2004, 20(6): 438-445.
  • 5Arterburn D, Schauer DP, Wise BE, et al. Change in predicted 10-year cardiovascular risk following laparoscopic Roux-en-Y gastric bypass surgery [J]. Obes Surg, 2009, 19(2): 184-189.
  • 6Flum DR, Belle SH, King WC, et al. Perioperative safety in the longitudinal assessment of bariatric surgery [J]. N Engl J Med, 2009, 361(5): 445-454.
  • 7Lynch R J, Eisenberg D, Bell RL. Metabolic consequences of bariatric surgery [J]. J Clin Gastroenterol, 2006, 40(8): 659-668.
  • 8Henry B, Yoav A, Eugene B, et al. Bariatric surgery: A systematic review and meta-analysis [J]. JAMA, 2004, 292 (14): 1724-1737.
  • 9Buchwald H, Estok R, Fahrbach K, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis [J]. Am J Med, 2009, 122(3): 248-256.
  • 10Sjostrom L, Lindroos AK, Pehonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery [J]. NEJM, 2004, 351 (26): 2683-2693.

共引文献161

同被引文献107

  • 1Abd Elrazek Mohammad Ali Abd Elrazek,Abduh Elsayed Mohamed Elbanna,Shymaa E Bilasy.Medical management of patients after bariatric surgery: Principles and guidelines[J].World Journal of Gastrointestinal Surgery,2014,6(11):220-228. 被引量：10
  • 2郑成竹,李际辉.中国肥胖病外科治疗指南(2007)[J].中国实用外科杂志,2007,27(10):759-762. 被引量：170
  • 3中华医学会糖尿病学分会, 中华医学会外科学分会. 手术治疗糖尿病专家共识. 中华糖尿病杂志 2011; 3: 205-208.
  • 4GREGG E W, CHENG Y J, NARAYAN K M, et al. The relative contributions of different levels of overweight and obesity to the increased prevalence of diabetes in the United States: 1976-2004[J]. Prev Med, 2007, 45(5): 348-352.
  • 5YANG W, LU J, WENG J, et al. Prevalence of diabetes among men and women in China~J~. N Engl J Med, 2010, 362(12) ~ 1090-1101.
  • 6PERRY I J, WANNAMETHEE S G, WALKER M K, et al. Prospective study of risk factors for development of non- insulin dependent diabetes in middle aged British men[J]. BMJ, 1995, 310(6979): 560-564.
  • 7ZIMMET P, ALBERTI K G, SHAW J. Global and societal implications of the diabetes epidemic[J]. Nature, 2001, 414 (6865) : 782-787.
  • 8BROOK R D, BARD R L, RUBENFIRE M, et al. Useful- ness of visceral obesity (waist/hip ratio) in predicting vascu- lar endothelial function in healthy overweight adultsFJ3. AmJ Cardiol, 2001, 88(11)~ 1264-1269.
  • 9PORIES W J, SWANSON M S, MACDONALD K G, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitusI-J~. Ann Surg, 1995, 222(3): 339-350.
  • 10SCHAUER P R, BURGUERA B, IKRAMUDDIN S, et al. Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus[J]. Ann Surg, 200a, 238(4): 467-484.

引证文献7

二级引证文献59

中华糖尿病杂志
2014年 第3期

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