摘要
目的探索慢性前列腺炎的细菌感染情况,为指导临床合理用药寻找依据。方法对146例慢性前列腺炎的前列腺液标本进行细菌学及支原体的培养分离,并对主要致病菌进行药敏试验。结果 146例前列腺液标本中共有117例呈阳性,阳性率80.14%。其中革兰氏阳性菌75株占64.10%;革兰氏阴性菌13株占11.11%;支原体14株占11.97%;真菌类5株占4.27%;混合感染10株占8.55%。葡萄球菌属中敏感性最好的是万古霉素与替考拉宁,三代头孢、喹诺酮类药物对病原葡萄球菌、大肠埃希菌敏感性尚可;克拉霉素(CLA)对解脲支原体(UU)效果最好,人型支原体(MH)对交沙霉素(JOS)敏感。结论细菌性感染可能仍为慢性前列腺炎的主要病因,葡萄球菌及支原体的感染应同时引起临床注意并以细菌培养及药敏结果正确指导用药,对彻底治疗及避免耐药菌株产生有重要意义。
Objective To investigate the pathogen distribution and antibiotic resistantce of chronic prostatitis, and to provide basis for rational drag use in clinic. Methods Mycoplasma and bacteria from 146 prostatic fluid samples of chronic protstitis patients were cultured and separated, and the main pathogens were conducted drug sensitivity test. Results There were 117 positive samples in the 146 prostatic fluid samples （80. 14% ）, including 75 strains of gram positive bacteria （64.10%）, 13 strains of gram negative bacterium （11.11% ）, lg strains of mycoplasma（ 25.5 % ）, 5 strains of fungi （4.27%）, and 10 mixed infection strains（8.55% ）. Staphylococcus was highly sensitive to vancomycin and teicoplanin, while moderately sensitive to the third - generation cephalosporin and quinolones. Ureaplasma urealyticum was sensitive to clarithromycin, and mycoplasma homi- nis was sensitive to josamycin. Conclusion Bacterial infection may be still the dominant cause of chronic pretatitis. Both Staphylococcus infection and mycoplasma infection should be given rational clinical medication based on bacterial culture and drug sensitivity results, so as to avoid the drag- resistant strains and realize radical therapy.
出处
《中国卫生检验杂志》
北大核心
2014年第6期851-852,857,共3页
Chinese Journal of Health Laboratory Technology
关键词
前列腺炎
支原体
细菌
抗生素
Prostatitis
Mycoplasma
Bacterium
Antibiotics
