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清洁手术预防使用抗菌药物对术后感染的影响研究 被引量:9

Study on effect of prophylactic antibiotic usage for clean surgical operation on postoperative infection
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摘要 目的探讨清洁手术预防使用抗菌药物对术后感染的影响,以期规范抗菌药物应用。方法回顾性分析2011年1月-2013年9月医院的Ⅰ类切口手术、经血管途径介入诊断手术、白内障、腹股沟疝修补术、甲状腺、乳腺手术患者,自2012年起开展了规范性管理,观察以上手术术后感染情况,采用SPSS13.0软件进行统计分析。结果 2011、2012、2013年Ⅰ类切口手术抗菌药物使用率分别为91.0%、35.6%、28.1%,呈逐年下降趋势,差异有统计学意义(P<0.05);2011、2012、2013年Ⅰ类切口手术感染率均为0.6%,差异无统计学意义。结论预防使用抗菌药物要严格掌握适应证,避免滥用,更好地发挥抗菌药物的临床效果。 OBJECTIVE To explore effect of prophylactic antibiotic usage for clean surgical operation on postopera- tive infection in order to standardize the clinical application of antibacterial drugs. METHODS A retrospective analysis was conducted on patients undergoing type I incision operation, intra-vessel interventional diagnosis operation, surgery for cataract, inguinal herniorrhaphy as well as surgeries for thyroid and breast cancer in our hospital during Jan. 2011 to Sept. 2013. As standardized clinical management was applied since 2012, the patients were observed for infections after the above operations. The software SPSS 13.0 was used for statistical analysis. RESULTS The usage rate of antibiotics for type I incision operation in the year 2011, 2012, and 2013 was 91.0%, 35.6 %, and 28.1%, showing a decreasing tendency by year, with significant differences (P〈0.05). The infec- tion rate for type Ⅰ incision operation in the year 2011, 2012, and 2013 was all 0.6%. CONCLUSION The prophy- lactic use of antibiotics should be strictly controlled in regard to indications, and antibiotic abuse should be avoided in order to increase clinical effect of antibiotic prophylaxis.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2014年第8期1877-1878,1884,共3页 Chinese Journal of Nosocomiology
基金 广西科学研究与技术开发计划基金项目(桂科攻0993003B-29)
关键词 预防 抗菌药物 清洁手术 术后感染 影响性 Prevention Clean surgical operation Postoperative infection Influence
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  • 1余爱荣,辛华雯,吴笑春.整治前后颅脑清洁手术围手术期预防用抗菌药应用调查[J].中国药师,2012,15(3):393-396. 被引量:7
  • 2曹军,刘洪阳,何阳,等.血管介入治疗预防性应用抗菌药物对术后感染发生率影响的临床研究[J].临床和试验医学杂志,2013,12(12):924-925.
  • 3Mitra, Anindita, Pramanik, et al. Phylogeny, phenotypic and nutritional characteristics of estuarine soil actinomycetes hav ing broad-spectrum antimicrobial activity derived from an eco logically guided bioprospecting programme[J]. World Journal o{ Microbiology amp Biotechnology, 2011, 27 (7): 1679 1688.

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