摘要
采用固相萃取-液相色谱-串联质谱技术（SPE-LC-MS/MS）建立了同时测定纺织品中三氯生和三氯卡班的分析方法.样品用二氯甲烷超声提取,C18固相萃取净化后分析.串联质谱在多反应监测（MRM）模式下检测目标分析物,以保留时间和特征离子对（母离子和碎片离子）信息比较进行定性和定量分析.三氯生和三氯卡班的线性范围分别为1.0 ～50.0、0.25 ～ 50.0 ng/mL.本方法的定量限分别为1.0和0.25 μg/kg,平均回收率为84.5％～108.2％,相对标准偏差小于8.1％.结果表明该方法准确、灵敏,可用于纺织品中三氯生和三氯卡班的分析测定.
A method for simultaneous determination of triclosan and triclocarban in textiles was developed by solid phase extraction and liquid chromatography-mass spectrometry （SPE-LC-MS/MS）. The sample was extracted with dichloromethane by ultrasonic wave and purified on a C18 SPE cartridge. The analyte was determined by an electrospray ionization-mass spectrometry in multiple reactions monitoring （MRM） mode. The qualitative and quantitative analyses were based on the retention times and characteristic ion pairs consisting of one parent ion and fragment ions of the analyte. Linearities for triclosan and triclocarban were in the range of 1.0 - 50.0 and 0.25 - 50.0 ng/mL, respectively. The limits of quantification （LOQs） for triclosan and triclocarban were 1.0 and 0.25 ug/kg, respectively, and the average recoveries were in the range of 84.5% - 108.2% with the relative standard deviations below 8. 1%. This method is accurate and sensitive, and is suitable for the analysis of triclosan and triclocarban in textiles.
出处
《纺织学报》
EI
CAS
CSCD
北大核心
2014年第4期71-74,共4页
Journal of Textile Research
基金
国家级公益性行业科研专项(201110041)
关键词
液相色谱-串联质谱
固相萃取
三氯生
三氯卡班
liquid chromatography-tandemed mass spectrometry
solid-phase extraction
triclosan
triclocarban
textiles
