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发热儿童血PCT水平及其与CRP和WBC的关系

Correlation between procalcitonin levels and C-reactive protein and white blood cell count in febrile children
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摘要 目的:研究发热儿童血降钙素原(PCT)水平及其与C反应蛋白(CRP)及WBC的关系。方法:收集2012年1月至2013年5月中山大学孙逸仙纪念医院收治的32例急性发热儿童作为研究对象。根据血WBC水平分为A组16例(WBC升高);B组为16例(WBC正常或降低)。收集年龄、性别相匹配的32例健康儿童为正常对照组。检测血PCT、CRP及WBC水平。结果:A组患者血PCT水平高于B组和正常对照组(P<0.05);A组患者血CRP水平高于正常对照组(P<0.05);B组血PCT、CRP水平明显高于正常对照组(P<0.05)。A组患者血PCT水平与CRP、WBC水平呈正相关关系(r=0.68,r=0.76,P<0.05);而B组血PCT水平与CRP、WBC水平无相关关系(P>0.05)。结论:发热儿童血PCT升高伴随血WBC升高,二者具有正相关关系。 Objective:To investigate the relationship of procalcitonin (PCT) levels with C-reactive protein (CRP) and white blood cell count (WBC) in febrile children. Methods: Between January 2012 and May 2013, we recruited 32 febrile children from the department of medical laboratory testing, Sun Yat-sen Memorial Hospital. Children were allocated to group A (n = 16, characterized by increased WBC) and group B (n = 16, characterized by normal or decreased WBC). We also enrolled 32 healthy children as the control group. This entailed measurement of the levels of PCT, CRP and WBC. Results: The levels of PCT (4.06 ±0.79 ) μg/L) and CRP (46.3 ± 19.3 )mg/L were highest in group A, followed by group B and normal control group( all P 〈 0.05 ). In group A, there was a positive correlation between PCT and CRP or WBC ( r = 0.68 and 0.76, both P 〈 0.05 ). However, these relations were absent in group B ( all P 〉 0.05 ). Conclusion : The increased levels of PCT which are accompanied by augmented WBC in febrile children are positively correlated with each other.
出处 《广州医学院学报》 2013年第5期81-83,共3页 Academic Journal of Guangzhou Medical College
关键词 降钙素原 C反应蛋白 白细胞 发热 急性 Procalcitonin C-reactive protein white blood cell fever acute
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