摘要
目的:研究胎盘植入治疗中使用甲氨蝶呤联合米非司酮的治疗效果,以更好地为胎盘植入患者进行治疗。方法:对2008年2月-2013年5月云南省德宏州人民医院收治的胎盘植入患者29例进行试验,所有患者均采用甲氨喋呤联合米非司酮治疗,观察患者的疗效,并监测其血β-hCG水平。结果:15例患者治疗1周内植入胎盘完全自行剥离;8例患者治疗1周后血β-hCG明显降低,治疗1个月内植入胎盘完全自行剥离;5例患者治疗2个月内植入胎盘完全自行剥离(其中1例患者产后出现发热为耐药菌感染);1例患者治疗2个月后血β-hCG明显降低,但部分残留胎盘未排出,给予宫腔镜治疗切除残留胎盘后治愈,术后复查血β-hCG正常,随访3个月发现患者子宫恢复正常。结论:对胎盘植入患者给予甲氨蝶呤联合米非司酮治疗具有较好的效果,值得应用。
Objective： To explore the effect of placenta implantation by methotrexate combined with mifepristone tablets, to better serve the patients were treated with placenta implantation.Method： 29 eases with placenta implantation from February 2008 to May 2013 in Dehong People＇s Hospital were selected as experiment subjects, all patients were treated with methotrexate combined with mifepristone tablets, observation of patients, and the measurement of serum β -hCG level.Result： After a week 15 cases into the placenta completely self release, 8 cases after 1 week of treatment, serum β-hCG was significantly lower in 1 month, treatment of placenta accreta is completely self release.After 2 months 5 cases the placenta completely self release（including 1 case of patient with postpartum fever for drug resistant bacteria infection of 1 case）.After 2 months the blood β-hCG decreased significantly, but some residual placenta not discharge.Given the hysteroscopic treatment cured after resection of residual placenta.Postoperative blood β -hCG was normal.Follow up 3 months found in patients with uterine recove. Conclusion： The treatment has a better effect on placental implantation with methotrexate combined with mifepristone tablets, it is worth of application.
出处
《中外医学研究》
2014年第10期18-20,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
胎盘植入
保守治疗
甲氨蝶呤
米非司酮
Placenta implantation
Conservative treatment
Methotrexate
Mifepristone tablet
