摘要
目的探讨新生儿呼吸机相关性肺炎(VAP)感染的危险因素以及病原学分析。方法回顾分析95例接受机械通气危重新生儿的临床资料。结果 VAP的感染率为36.84%(35/95)。不同胎龄、出生体重和通气持续时间与VAP发生有关(P<0.05或0.01)。病原菌多为革兰阴性杆菌(75.6%),其中前三位分别为肺炎克雷伯菌(26.8%),大肠埃希菌(22.0%)和鲍氏不动杆菌(12.2%),多为耐药菌。结论 VAP发生率高,应减少和监控危险因素,依据病原学及药敏结果合理用药。
Objective To study the risk factors and the pathogen of neonatal ventilator-associated pneumoni-a.Methods A retrospective analysis of clinical data of 95 neonates patients who accepted mechanical ventilation was conducted.Results The infection incidence rate of ventilator-associated pneumonia（VAP） was 36.84%（35/95）. Statistical analysis showed that different gestational age , birth weight and ventilation duration were the risk factors as-sociated with the development of VAP （ P〈0.05 or P〈0.01 ） .Main pathogenic bacteria were gram negative bacilli （75.6%）, of which the first three kinds were Klebsiella pneumoniae （26.8%）, Escherichia coli（22%） and Acine-tobacter baumannii （12.2%） and most of them were drug resistant bacteria .Conclusion The incidence rate of VAP in neonates high , the risk factors should been reduced and controled , rational use of drugs is done according to patho-gens and drug sensitivity results .
出处
《中国临床新医学》
2014年第3期240-242,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
新生儿
呼吸机相关肺炎
高危因素
耐药
Neonate
Ventilator associated pneumonia（VAP）
Risk factors
Drug resistance
