摘要
目的观察口服与静脉吗啡滴定治疗重度癌性疼痛的效果及安全性。方法选取35例重度癌痛患者分为两组,口服组(16例)采用口服盐酸吗啡片治疗,静脉组(19例)采用静脉注射吗啡注射液治疗。结果静脉组滴定后15、30、60、90、120 min的止痛有效率均高于口服组,差异有统计学意义(P<0.05)。两组滴定后的总有效率、不良反应发生率比较,差异无统计学意义(P>0.05)。两组治疗后的生活质量评分低于治疗前,差异有统计学意义(P<0.05);两组治疗后的生活质量评分比较,差异无统计学意义(P>0.05)。结论口服及静脉注射吗啡对重度癌痛患者进行滴定均起效迅速,疗效确切,不良反应少,安全性高,能有效提高患者的生活质量,同时通过规范化护理,使滴定方案顺利完成,提高患者癌痛控制满意度。
Objective To observe the curative effect and security of oral and intravenous morphine titration in the treatment of severe pain. Methods 35 patients with severe pain were divided into two groups,oral morphine hydrocblo- ride tablet was used in oral group （16 cases）,intravenous morphine injection was used in intravenous group （19 cases）. Results Effective analgesic rate of intravenous group after 15,30,60,90,120 min was higher than that of oral group re- spectively,with statistical difference （P〈0.05）.Total efficiency,the incidence of adverse reaction in two groups was com- pared respectively,with no statistical difference （P〉0.05）.Quality of life score in two groups after treatment was lower than before treatment respectively,with statistical difference （P〈0.05）.Quality of life score in two groups after treatment was compared,with no statistical difference （P〉0.05）.Conclusion Oral and intravenous injection of morphine in patients with severe pain titration are more quickly,have curative effect,less adverse reaction and high safety,can improve the patients quality of life.Through standardization of nursing at the same time,titration scheme could complete smoothly and could improve the satisfaction of patients pain control.
出处
《中国当代医药》
2014年第11期136-139,共4页
China Modern Medicine
基金
广东省江门市科技局科研立项项目(江科[2012]108号-21)
关键词
口服
静脉吗啡滴定
重度癌痛
护理
Oral/intravenous morphine titration
Severe cancer pain
Nursing
