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早期应用米力农在重症手足口病的临床研究 被引量:8

Clinical study of early application of Milrinone in patients with severe hand foot and mouth disease
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摘要 目的观察早期应用米力农治疗重症手足口病的临床疗效。方法将200例重症手足口病患儿随机分为两组,将患儿进行临床分期,观察并分析临床疗效。结果治疗组患儿体温、呼吸、心率、血压恢复正常所需时间较对照组患儿明显缩短,差异均有统计学意义(P<0.05)。治疗组100例有3例转为危重症,占3%,对照组100例有9例转为危重症,占9%,差异有统计学意义(P<0.05)。结论早期应用米力农治疗重症手足口病能明显改善心肺功能,减少神经源性肺水肿及呼吸循环衰竭的发生率,改善预后及缩短治疗时间。 [Objective] To investigate the clinical effects on children's severe hand- foot- mouth disease treated by Milrinone. [Methods ] 200 cases of severe hand- foot- mouth disease patients were randomly di- vided into two group, and implement clinical stages were further carried out to observe and analyze the clini- cal effects. [Results] The treatment group with body temperature, respiration, heart rate, blood pressure re- turned to normal time needed for the control group with significantly reduced, the difference had statistical significance (P〈0.05). Treatment group 100 cases in 3 cases to critically ill, accounted for 3%, control group, 100 cases of nine to critically ill, accounted for 9%, the difference was statistically significant (P 〈0.05). [Conclusion] Early treatments with Milrinone for severe hand foot mouth disease can significantly improve heart function, reduce neurogenic pulmonary edema, the incidence of respiratory and circulatory failure, im- prove the prognosis and shorten the period of treatment.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2014年第5期107-109,共3页 China Journal of Modern Medicine
关键词 米力农 手足口病 治疗 Milrinone hand -foot-mouth disease treatment
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  • 1马洪林.米力农在慢性肺心病心力衰竭治疗中的作用[J].临床荟萃,2006,21(16):1197-1198. 被引量:10
  • 2李树政 李家宜 等.小儿心力衰竭的诊断治疗方案(试行)[J].中华儿科杂志,1985,23:295-296.
  • 3Shipley JB, Tolman D, Hastillo A, et al. Milrinone: basic and clinical pharmacology and acute and chronic management[J]. Am J Med Sci,1996,311(6):286-291.
  • 4Lanfear DE,Hasan R, Gupta RC, et al. Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure[J].J Transl Med, 2009,67 (7) : 1-6.
  • 5Zewail AM,Nawar M, Vrtovec B, et al. Intravenous milrinone in treatment of advanced congestive heart failure [J]. Tex Heart Inst J,2003,30(2):109-113.
  • 6Albrecht CA,Giesler GM, Kar B, et al. Intravenous milrinone infusion improves congestive heart failure caused by diastolic dysfunction:a brief case series[J]. Tex Heart Inst J, 2005,32 (2) :220-223.
  • 7Gorodeskl EZ, Chu EC, Reese JR, et al. Prognosis on chronic dobutamine or milrinone infusions for stage D heart failure[J]. Circ Heart Fail,2009,2(4) :320-324.
  • 8Givertz MM, Hare JM, Lob E, et al. Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction., a rapid test for reversibility of pulmonary hypertension [J]. J Am Coll Cardiol,1996,28(7) :1775- 1780.
  • 9Cai J,Su Z,Shi Z,et al. Nitric oxide and milrinone: combined effect on pulmonary circulation after Fontan-Type procedure..a prospective, randomized study[J]. Ann Thorae Surg, 2008,86 (3) :882-888.
  • 10Lakshminrusimha S, Porta NF, Farrow KN, et al. Milrinone enhances relaxation to prostacyclin and iloprost in pulmonary arteries isolated from iambs with persistent pulmonary hypertension of the newborn[J]. Pediatr Crit Care Med, 2009, 10(1):106- 112.

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