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系统性恶性肿瘤所致脑膜癌病的磁共振成像表现 被引量:46

MR imaging of meningeal carcinomatosis by systemic malignancy
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摘要 目的 探讨脑膜癌病的MRI表现特点 ,提高对脑膜癌病的影像学认识和诊断水平。方法 经确诊的脑膜癌病 11例 ,MR常规扫描后均行钆喷替酸葡甲胺 (Gd DTPA)增强扫描 ,对其增强特点及病变类型进行了回顾性分析。结果 MR平扫均未见脑膜异常信号。增强扫描后 9例显示软脑膜异常增强 ,表现为脑表面连续的、可延伸至脑沟内的细线状高信号 ,累及范围包括小脑、脑干及大脑表面 ,但未见明确的蛛网膜下腔异常增强。 3例显示硬脑膜 蛛网膜异常增强 ,表现为大脑凸面或小脑幕等处连续的、较粗的弧线状高信号 ,该信号不延伸至脑沟内 ,3例均累及大脑凸面 ,其中 1例同时累及小脑凸面和小脑幕。 9例累及软脑膜者脑脊液均为异常 ,2例仅累及硬脑膜 蛛网膜者脑脊液均为正常。结论 MR增强扫描能很好地显示脑膜癌病 ,根据增强特点可以区分脑膜癌病的类型 。 Objective To investigate the MR features of meningeal carcinomatosis, and to improve the ability in understanding and diagnosing meningeal carcinomatosis by MR findings. Methods Eleven cases with proven meningeal carcinomatosis were studied by conventional and Gd DTPA enhanced MR imaging. The enhancement patterns and features, as well as the types of meningeal involvement, were retrospectively analyzed. Results Conventional MR imaging showed no evident meningeal abnormalities. After the administration of Gd DTPA, abnormal pia mater enhancement was detected in 9 cases, demonstrating as the continuous, thin, and lineal high signal intensity on the brain surface that could descend into the sulci. The abnormal pial enhancement occurred on the cortical surfaces of cerebellum, brainstem, and cerebrum. No abnormal enhancement in the subarachnoid space was found. Abnormal dura arachnoid enhancement was seen in 3 cases, showing as the continuous, thick, and curvilineal high signal intensity over the convexities or in the tentorium without extension into the cortical sulci. Cerebral dura arachnoid involvement was found in all 3 cases and one of them also showed abnormal enhancement in cerebellar dura arachnoid and tentorium. Of the 11 cases, 9 with pial involvement had abnormal CSF results, 2 involving only the dura arachnoid had normal CSF results. Conclusion Meningeal carcinomatosis could be well demonstrated by Gd DTPA enhanced MR imaging, and its type could be differentiated by the enhancement features. Combined with the clinical information, Gd enhanced MR imaging may lead to the diagnosis and guide the therapy.
出处 《中华放射学杂志》 CAS CSCD 北大核心 2001年第1期11-14,共4页 Chinese Journal of Radiology
关键词 脑膜肿瘤 肿瘤转移 磁共振成像 脑膜癌病 Meningeal neoplasms Neoplasm metastasis Magnetic resonance imaging
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  • 1Lee Y Y,AJR,1990年,154卷,351页

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