摘要
目的探究慢性心力衰竭(CHF)患者的血红蛋白降低与其心肾功能下降的关系。方法选取165例住院患者为实验组,按心功能分级为3组(II:55例,III:50例,IV:60例),并随机选同期30例老年健康体检者作对照组,根据CHF患者血红蛋白水平再分为贫血组(68例)和非贫血组(97例),对比不同组心肾功能指标差异性。结果 CHF各组的贫血率皆比对照组高(P<0.05);CHF各分组心、肾功能和血液学指标比对照组呈不良趋势;比较贫血组与非贫血组的心肾功能,贫血组Scr和GFR相对升高,LVEF水平明显下降,LVEDd明显增大(P<0.05)。结论慢性心衰患者血红蛋白水平的降低与心肾功能的下降相关,血红蛋白水平越低,心肾功能受影响越严重。
Objective To study the changes of hemoglobin （Hb） level, cardiac function and renal function in patients with chronic heart failure （CHF）. Methods A total of 165 male CHF patients were enrolled into the study and classified into three group ： class II group （55 cases）, class III group （50 cases） and class IV group （60 cases）. Another 30 healthy subjects in the same period were randomly selected as the member of healthy control group. Additionally, based on patients＇ HB level, they were divided into anemia CHF group （68 cases） and non - anemia CHF group （ 97 cases）. Correlative indexes of cardiac function and renal function in all groups were colleted and compared between different groups. Results In all CHF groups, the morbidity of anemia were obviously higher than that of the healthy con- trol group;compared to the hea]thy control group,the indexes of cardiac function （LVEDd, LVEF） , of renal function （SCr, GFR ） and of hematology （Hb） in all CHF groups showed significant aggravation. Compared with non - anemia CHF group, the level of Ser , GFR and LVEF decreased significantly, but LVEDd in CHF anemia group increased significantly （ P 〈 0.05 ）. Conclusion Descent in HB level may significantly have a negative effect on cardiac and renal function in patients with CHF and the exacerbation of cardiac and renal function may have some relationship with the decreasing HB level .
出处
《黑龙江医学》
2014年第3期288-289,共2页
Heilongjiang Medical Journal
关键词
慢性心力衰竭
血红蛋白
心功能
肾功能
Chronic heart failure
Hemoglobin
Cardiac function
Renal function
