摘要
创面愈合是一个复杂的生物学过程，需要有活力的各种细胞、细胞因子、生长因子及胶原蛋白等的相互作用。大面积烧伤患者往往因为创面感染导致机体发生脓毒症和MODS等严重并发症，不仅影响机体各器官的功能，也影响了创面愈合的过程。有关烧伤并发脓毒症后对心、肺等脏器功能的影响已有较多研究，但对创面愈合影响的研究甚少。
Sepsis is considered as an uncontrolled in- flammatury response, while wound healing is a process involving the joint participation of many elements, including inflammatory cells, repair cells, inflammatory mediators, growth factors, and extracellular matrix. This review summarizes the effects of chan- ges in immune function, coagulation function, and metabolism after sepsis as a complication of burn on wound healing, and looks into the prospect of prevention and treatment of burn com- plicated by sepsis, hoping to accelerate wound healing by reduc- ing the incidence of sepsis.
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2014年第2期137-140,共4页
Chinese Journal of Burns
