摘要
目的 探讨脑胶质瘤病 (GC)的诊断和治疗。方法 对本院神经外科 1982～ 1997年间收治的 13例GC进行回顾性研究。结果 GC临床表现以头痛 (11/ 13)和癫痫 (4 / 13)为常见 ,后期多出现严重颅高压征象。病灶弥漫性生长 6例 ,多发性生长 7例。 9例行开颅手术 ,3例行立体定向穿刺活检 ,1例行尸检。病理诊断 :星形胶质瘤Ⅰ级 7例 ,星形胶质瘤Ⅰ～Ⅱ级 2例 ,星形胶质瘤Ⅱ级 2例 ,少枝胶质瘤Ⅰ级 1例 ,少枝 星形混合胶质瘤Ⅱ级 1例。平均生存期为 5 75月。结论 讨论了GC的发生、临床表现、影像学特点、病理特点。
Objective To characterize the diagnosis and treatment of gliomatosis cerebri (GC). Methods Clinical studies of 13 patients with GC (1982 1997) were reviewed retrospectively. Results The main clinical presentation of the 13 cases included headache (11/13), seizure (4/13), and sign of evaluated intracranial pressure later. The tumor involved at least 2 lobes of brain in all patients, in which diffused infiltration in 6 cases and multiple lesions in 7 cases. Nine cases underwent partially surgical removal of the tumor lesions and 3 cases underwent stereotactic biopsy. The Pathologic diagnosis were low grade astrocytoma (grade Ⅰ～Ⅱ) in 11, grade I oligodendrocytoma in 1, and both mixture in 1. The mean lifetime was 5 75 months. Conclusions The tumorigenesis, clinical presentation, characters of CT and MRI images, pathological classification, therapy and prognosis of GC were discussed.
出处
《中华神经外科杂志》
CSCD
北大核心
2001年第1期7-10,共4页
Chinese Journal of Neurosurgery
关键词
脑肿瘤
胶质瘤
立体定向术
治疗
Gliomatosis cerebri Stereotactic biopsy Diagnosis
