摘要
目的 检测变态反应病患者血清 Ig E的水平及变应原皮试并分析其临床意义 .方法 应用酶联免疫吸附分析法检测了 15 0例正常人与 2 2 3例变态反应病患者血清 Ig E水平 .结果 结果表明 :1正常人血清 Ig E水平随年龄增长而下降 (P<0 .0 1) ,2各年龄组 (≤ 2 0岁、2 1～ 40岁和≥ 40岁 )变态反应病患者血清 Ig E水平均高于对照组 ;3吸入性变态反应病患者血清 Ig E水平明显高于同年龄正常对照组 (P<0 .0 1) ,与皮试结果有高度一致性 .结论 血清 Ig E水平测定对变态反应病的诊断具有重要意义 ,与皮试联合应用 。
AIM to evaluate clinical significance of serum IgE levels and allergen skin test in allergic patients. METHODS Serum IgE levels of 223 allergic patients and 150 health volunteers were detected by ELISA, and skin test of the patients was performed with certain allergens. RESULTS ① the serum IgE levels of health volunteers declined with the increase of their age ( P <0.01); ② Serum IgE levels of thepatients at all age groups were significantly higher than those of normal controls in the same age group ( P <0.01); ③ Serum IgE levels of the patients with inhalant allergy obviously increased as compared with control at the same age groups ( P <0.01), and the results of in vivo skin test with the detection of serum IgE levels were in high concordance. CONCLUSION Detection of the serum IgE levels is highly sensitive and specific for diagnosis of most inhalant allergy, and might be more valuable when combined with allergen skin test as well as comprehensive clinical analysis.
出处
《第四军医大学学报》
北大核心
2001年第4期344-346,共3页
Journal of the Fourth Military Medical University
