摘要
目的:探讨透明帽辅助下食管静脉曲张硬化治疗的临床疗效与安全性.方法:78例肝硬化患者采用硬化剂治疗食管曲张静脉,分成内镜下直接注射治疗组(A组,n=47),透明帽辅助下注射治疗组(B组,n=31)治疗后1、6、12 mo行胃镜检查,比较食管曲张静脉治疗后改变、内镜治疗所需时间及术后不良反应发生率.结果:透明帽辅助组的食管曲张静脉治疗有效率高于直接注射治疗组(B组96.8%,A组74.5%,P<0.05),硬化剂使用量减少(A组80.54mL±18.72 mL,B组60.54 mL±12.74 mL P<0.05)及治疗次数减少(A组4.78次±1.24次B组2.78次±1.24次,P<0.05),内镜下治疗时间缩短(A组8.26 min±1.45 min,B组5.27 min±1.63 min,P<0.05),治疗周期缩短(A组29.31 d±6.29 d,B组20.20 d±4.79 d,P<0.05),并发症的发生率减少(A组48.9%,B组38.7%).结论:初步研究发现透明帽辅助下食管静脉曲张硬化治疗能降低术中出血风险、提高疗效.
AIM： To evaluate the efficacy and safety of hood- assisted endoscopic esophageal injection sclero- therapy （EIS） in cirrhotic patients with esopha- geal varices. METHODS： Seventy-eight cirrhotic patientswith esophageal varices treated by EIS were divided into two groups： 47 patients （group A） were treated by direct injection and 31 by hood- assisted endoscopy （group B）. The changes in endoscopic characteristics of esophageal varices, the time required to perform endoscopic treat- ment, and other complications were compared between the two groups. The patients were fol- lowed 1, 6, and 12 mo after treatment. RESULTS： The hood-assisted EIS method might improve efficacy compared with the direct injec- tion group （group B： 96.8% vs group A： 74.5%, P 〈 0.05）. The smaller volume of sclerosant was re- quired to eradicate varices in the hood-assisted EIS group （80.54 mL ± 18.72 mL vs 60.54 mL ± 12.74 mL, P 〈 0.05）. The sessions of sclerother- apy （4.78 times ± 1.24 times vs 2.78 times ± 1.24 times, P 〈 0.05）, the time required to perform endoscopic treatment （8.26 min ± 1.45 min vs 5.27 min ± 1.63 min, P 〈 0.05） and the incidence of complications were significantly reduced in the hood-assisted group. C O N C L U SlO N： Our preliminary results indicate that the hood-assisted EIS method may reduce the risk of variceal bleeding during EIS and im- prove the efficacy of EIS.
出处
《世界华人消化杂志》
CAS
北大核心
2014年第6期837-841,共5页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
Nos.81070337
81271736
安徽省教育厅自然科学重点研究基金资助项目
No.KJ2012Z189
安徽省卫生厅医学科研课题基金资助项目
No.2010B018~~
关键词
食管和胃静脉曲张
出血
硬化剂治疗
透
明帽辅助
Esophageal and gastric varices
Bleeding
Esophageal injection sclerotherapy
Hood-assisted
