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水蛭栓剂治疗精液不液化50例临床效果观察 被引量:5

Clinical efficacy of leeches suppositories for semen non-liquefaction:a clinical study of 50 cases
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摘要 目的探讨水蛭栓剂治疗精液不液化的临床疗效。方法 100例精液不液化的患者随即分为治疗组和对照组各50例,治疗组给予水蛭栓剂直肠给药,早晚各1次,对照组给予α-糜蛋白酶5 mg肌注,1次/d,两组患者均进行4周的治疗。结果治疗组精子活力明显高于对照组[(56.74±13.53)%vs(36.64±14.45)%],而精液液化时间明显低于对照组[(39.34±4.74)min vs(54.82±5.33)min],治疗后治疗组ACP[(11.52±2.45)μ/ml vs(6.14±1.28)μ/ml]和PSA[(233.63±23.46)mg/L vs(196.14±28.53)mg/L]水平明显高于对照组,治疗组治愈率(64.00%)和有效率(86.00%)明显高于对照组,两组以上各指标比较差异均具有统计学意义(P<0.05)。结论水蛭栓剂能通过改善前列腺功能,显著缩短精液液化时间,值得临床推广。 Objective To investigate the clinical efficacy of leeches suppository in the treatment of semen non-liquefaction. Methods A total of 100 patients with semen non-liquefaction were randomly divided into treat- ment group (n=50) and control group (n=50). The treatment group was given leech suppository rectally, sooner or lat- er, while the control group received α-chymotrypsin 5 mg intramuscularly, once per day. The treatment course was 4 weeks in both groups. Results The sperm motility of the treatment group was significantly higher that of the control group [(56.74±13.53)% vs (36.64± 14.45)%], while the semen liquefaction time was significantly lower than the control group [(39.34±4.74) rain vs (54.82±5.33) rain]. After treatment, ACP [(11.52±2.45) p/ml vs (6.14±1.28)] p/ml] and PSA [(233.63±23.46) mg/L vs (196.14±28.53) mg/L levels were significantly higher in the treatment group, and the cure rate [(64.00)%], effective rate [(86.00)%] was significantly higher in the treatment group (P〈0.05). Conclusion Leech suppository can significantly shorten the semen liquefaction time by improving prostate function, which is worthy of promotion.
出处 《海南医学》 CAS 2014年第7期964-966,共3页 Hainan Medical Journal
基金 武汉市科技攻关计划(编号:201260523184-5)
关键词 水蛭 栓剂 精液不液化 Leeches Suppositories Semen non-liquefaction
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